Embryonic stem cells are derived from an embryo and exist in two different states: naive
(before implantation) and primed (after implantation). The embryonic stem cells represent an …

The human placenta is a transient organ that mediates essential feto-maternal interactions
that are critical for a successful pregnancy. Trophoblast cells are specialized placental …

Human induced pluripotent stem cells (iPSCs) could provide a valuable tool for the
production of specific somatic cell types for disease modeling or cell replacement …

Abstract ADNP encodes Activity-Dependent Neuroprotective Protein, whose de novo
heterozygous mutations cause Helsmoortel-Van der Aa Syndrome (HVDAS), a rare …

Pluripotent cells of the embryo have the remarkable ability to form all somatic tissues and the
germ line. Mice have long provided a framework for our understanding of this property of the …

The successful reprogramming of human somatic cells into induced pluripotent stem cells
(hiPSCs) represented a turning point in the stem cell research field, owing to their ability to …

Embryonic stem (ES) cells are derived from the inner cell mass (ICM) of preimplantation
embryos. ES cells exhibit two common characteristics: the ability to differentiate into all three …

Human pluripotent stem cells (hPSCs), which include human embryonic stem cells (hESCs)
and human induced pluripotent stem cells (hiPSCs), infinitely self-renew, and can …

Induced pluripotent stem cells (iPSCs) derived using integration-free reprogramming
approaches have improved the prospects of these cells for various biomedical applications …

Familial neurohypophyseal diabetes insipidus (FNDI) is a degenerative disease of
vasopressin (AVP) neurons. Studies in mouse in vivo models indicate that accumulation of …