PATIENT-SPECIFIC MODELLING OF SYNDROMIC AUTISM: UNCOVERING THE ROLE OF ADNP IN CHROMATIN DYSREGULATION

L Rizzuti - 2022 - air.unimi.it
Abstract ADNP encodes Activity-Dependent Neuroprotective Protein, whose de novo
heterozygous mutations cause Helsmoortel-Van der Aa Syndrome (HVDAS), a rare …

Analysis of reprogramming-associated alterations using an isogenic human stem cell system

C Haubenreich - 2022 - bonndoc.ulb.uni-bonn.de
Human induced pluripotent stem cells (iPSCs) could provide a valuable tool for the
production of specific somatic cell types for disease modeling or cell replacement …

A Comparative Study of Cell Culture Conditions during Conversion from Primed to Naive Human Pluripotent Stem Cells

I Romayor Arredondo, L Herrera, M Burón… - 2022 - addi.ehu.es
The successful reprogramming of human somatic cells into induced pluripotent stem cells
(hiPSCs) represented a turning point in the stem cell research field, owing to their ability to …

[图书][B] Human endogenous retrovirus H protects the genome of human embryonic stem cells from mutagenic retroelements activity

A Kondrashkina - 2022 - search.proquest.com
Human pluripotent stem cells (hPSCs), which include human embryonic stem cells (hESCs)
and human induced pluripotent stem cells (hiPSCs), infinitely self-renew, and can …

[PDF][PDF] Krishna Kumar Haridhasapavalan, Pradeep Kumar Sundaravadivelu, Vishalini Venkatesan, Ranadeep Gogoi 2, S. Sudhagar 2, Rajkumar P. Thummer

C Dey, K Raina, M Thool, P Adhikari - Molecular Players in iPSC …, 2022 - researchgate.net
Induced pluripotent stem cells (iPSCs) derived using integration-free reprogramming
approaches have improved the prospects of these cells for various biomedical applications …

Rostral Hypothalamic Differentiation With Minimal Exogenous Signals in Human Naive Induced Pluripotent Stem Cells

H Ozaki, H Suga, M Sakakibara, M Soen, N Miyake… - 2022 - researchsquare.com
Familial neurohypophyseal diabetes insipidus (FNDI) is a degenerative disease of
vasopressin (AVP) neurons. Studies in mouse in vivo models indicate that accumulation of …

[PDF][PDF] and Antonio del Sol

M Zheng, B Xie, S Okawa, SY Liew, H Deng - researchgate.net
Cellular conversion can be induced by perturbing a handful of key transcription factors (TFs).
Replacement of direct manipulation of key TFs with chemical compounds offers a less …

[PDF][PDF] 6These authors contributed equally* Correspondence: pan_guangjin@ gibh. ac. cn (GP), lai_liangxue@ gibh. ac. cn (LL)

Y Zhu, Z Zhang, N Fan, K Huang, H Li, J Gu, Q Zhang… - researchgate.net
Obtaining functional human cells through interspecies chimerism with human pluripotent
stem cells (hPSCs) remains unsuccessful due to its extremely low efficiency. Here, we show …

[PDF][PDF] Azimeh Akhlaghpour, Adeleh Taei, 2, 5 Seyyed Abolghasem Ghadami, 3 Zahra Bahadori, 2 Saeed Yakhkeshi, 2 Sepideh Molamohammadi, 2 Tahereh Kiani, 2 …

Human pluripotent stem cells (hPSCs) are commonly kept in a primed state but also able to
acquire a more immature naive state under specific conditions in vitro. Acquisition of naive …

Manipulation of nuclear architecture

KCK Wang, S Morgan, F Wu, CC Huang - US Patent 11,293,018, 2022 - Google Patents
2021-12-20 Assigned to THE BOARD OF TRUSTEES OF THE LELAND STANFORD
JUNIOR UNIVERSITY reassignment THE BOARD OF TRUSTEES OF THE LELAND …