Up-regulation of long noncoding RNA MBNL1-AS1 suppresses breast cancer progression by modulating miR-423-5p/CREBZF axis

J Fang, G Jiang, W Mao, L Huang, C Huang… - …, 2022 - Taylor & Francis
Breast cancer is the leading cause of cancer-related death among females, which is
required to be solved urgently. Recent studies have found significant changes in a large …

Role of lncRNA LIPE-AS1 in adipogenesis

A Thunen, D La Placa, Z Zhang, JE Shively - Adipocyte, 2022 - Taylor & Francis
Recent studies have identified long non-coding RNAs (lncRNAs) as potential regulators of
adipogenesis. In this study, we have characterized a lncRNA, LIPE-AS1, that spans genes …

DLX6-AS1: A long non-coding RNA with oncogenic features

S Ghafouri-Fard, S Najafi, BM Hussen… - Frontiers in Cell and …, 2022 - frontiersin.org
Long non-coding RNAs (lncRNAs) are a heterogeneous group of ncRNAs with characteristic
size of more than 200 nucleotides. An increasing number of lncRNAs have been found to be …

High temporal resolution RNA-seq time course data reveals widespread synchronous activation between mammalian lncRNAs and neighboring protein-coding genes

W Muskovic, E Slavich, B Maslen… - Genome …, 2022 - genome.cshlp.org
The advent of massively parallel sequencing revealed extensive transcription beyond
protein-coding genes, identifying tens of thousands of long noncoding RNAs (lncRNAs) …

The multifaceted actions of the lncRNA H19 in cardiovascular biology and diseases

D Busscher, RA Boon, RP Juni - Clinical Science, 2022 - portlandpress.com
Cardiovascular diseases are the leading cause of death and debility worldwide. Various
molecular mechanisms have been studied to better understand the development and …

Regioselectivity of an arachidonate 9S-lipoxygenase from Sphingopyxis macrogoltabida that biosynthesizes 9S, 15S-and 11S, 17S-dihydroxy fatty acids from C20 and …

SE Kim, J Lee, JU An, TH Kim, CW Oh, YJ Ko… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Lipoxygenases (LOXs) biosynthesize lipid mediators (LMs) as human signaling molecules.
Among LMs, specialized pro-resolving mediators (SPMs) are involved in the resolution of …

Short open reading frames (sORFs) and microproteins: an update on their identification and validation measures

AZX Leong, PY Lee, MA Mohtar, SE Syafruddin… - Journal of biomedical …, 2022 - Springer
A short open reading frame (sORFs) constitutes≤ 300 bases, encoding a microprotein or
sORF-encoded protein (SEP) which comprises≤ 100 amino acids. Traditionally dismissed …

Progress in expression pattern and molecular regulation mechanism of lncRNA in bovine mastitis

L Jia, J Wang, Z Luoreng, X Wang, D Wei, J Yang… - Animals, 2022 - mdpi.com
Simple Summary Bovine mastitis is an inflammatory disease of the mammary glands that
causes serious harm to cow health and huge economic losses. Susceptibility or resistance …

Germline genetic biomarkers to stratify patients for personalized radiation treatment

I Deichaite, A Hopper, L Krockenberger… - Journal of translational …, 2022 - Springer
Background Precision medicine incorporating genetic profiling is becoming a standard of
care in medical oncology. However, in the field of radiation oncology there is limited use of …

New Insights into lncRNAs in Aβ Cascade Hypothesis of Alzheimer's Disease

Y Hao, B Xie, X Fu, R Xu, Y Yang - Biomolecules, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common type of dementia, but its pathogenesis is not
fully understood, and effective drugs to treat or reverse the progression of the disease are …