Impact of androgen receptor activity on prostate-specific membrane antigen expression in prostate cancer cells
U Sommer, T Siciliano, C Ebersbach… - International Journal of …, 2022 - mdpi.com
Prostate-specific membrane antigen (PSMA) is an essential molecular regulator of prostate
cancer (PCa) progression coded by the FOLH1 gene. The PSMA protein has become an …
cancer (PCa) progression coded by the FOLH1 gene. The PSMA protein has become an …
Recent advances in medical therapy for urological cancers
T Yuasa, T Urasaki, R Oki - Frontiers in Oncology, 2022 - frontiersin.org
The mainstay of medical treatment has been tyrosine kinase inhibitors (TKIs) for renal cell
cancer (RCC), cytotoxic chemotherapy for urothelial cancer (UC), and androgen deprivation …
cancer (RCC), cytotoxic chemotherapy for urothelial cancer (UC), and androgen deprivation …
Study protocol and preliminary results from a mono-centric cohort within a trial testing stereotactic body radiotherapy and abiraterone (ARTO-NCT03449719)
G Francolini, B Detti, V Di Cataldo, P Garlatti… - La radiologia …, 2022 - Springer
Background ARTO trial was designed to evaluate the difference in terms of outcomes
between patients affected by oligo metastatic castrate resistant prostate cancer (mCRPC) …
between patients affected by oligo metastatic castrate resistant prostate cancer (mCRPC) …
Where do we stand in the management of oligometastatic prostate cancer? A comprehensive review
GR Juan, FH Laura, PV Javier, VC Natalia… - Cancers, 2022 - mdpi.com
Simple Summary Oligometastatic prostate cancer is an intermediate stage between
localised and metastatic disease. Today, there are many advances in the diagnosis of this …
localised and metastatic disease. Today, there are many advances in the diagnosis of this …
Survival modelling and cost-effectiveness analysis of treatments for newly diagnosed metastatic hormone-sensitive prostate cancer
Background In metastatic hormone-sensitive prostate cancer (mHSPC) treatment, survival
benefits have been shown by adding docetaxel or recent androgen receptor axis-targeted …
benefits have been shown by adding docetaxel or recent androgen receptor axis-targeted …
Rational second-generation antiandrogen use in prostate cancer
The second-generation antiandrogens have achieved an ever-growing list of approvals and
indications in subsets of prostate cancer. Here, we provide an overview of second …
indications in subsets of prostate cancer. Here, we provide an overview of second …
A novel artificial intelligence–powered method for prediction of early recurrence of prostate cancer after prostatectomy and cancer drivers
W Huang, R Randhawa, P Jain, S Hubbard… - JCO Clinical Cancer …, 2022 - ascopubs.org
PURPOSE To develop a novel artificial intelligence (AI)–powered method for the prediction
of prostate cancer (PCa) early recurrence and identification of driver regions in PCa of all …
of prostate cancer (PCa) early recurrence and identification of driver regions in PCa of all …
Spine stereotactic body radiotherapy for prostate cancer metastases and the impact of hormone sensitivity status on local control
A Abugharib, KL Zeng, CL Tseng, H Soliman… - …, 2022 - journals.lww.com
BACKGROUND: Stereotactic body radiotherapy (SBRT) is used to deliver ablative dose of
radiation to spinal metastases. OBJECTIVE: To report the first dedicated series of spine …
radiation to spinal metastases. OBJECTIVE: To report the first dedicated series of spine …
Prostate cancer treatment: 177Lu-PSMA-617 considerations, concepts, and limitations
O Sartor, K Herrmann - Journal of Nuclear Medicine, 2022 - Soc Nuclear Med
The phase III VISION trial using 177Lu-PSMA-617 has significant implications for the field of
theranostics and broad repercussions for the clinical management of prostate cancer …
theranostics and broad repercussions for the clinical management of prostate cancer …
A phase 1b adaptive androgen deprivation therapy trial in metastatic castration sensitive prostate cancer
Simple Summary Despite early utilization of new hormonal agents (NHA, ie, abiraterone,
enzalutamide and apalutamide) for combined androgen deprivation therapy (ADT) for …
enzalutamide and apalutamide) for combined androgen deprivation therapy (ADT) for …