Addition of new androgen receptor pathway inhibitors to docetaxel and androgen deprivation therapy in metastatic hormone-sensitive prostate cancer: a systematic …

F Fiorica, C Buttigliero, D Grigolato, M Muraro, F Turco… - Current …, 2022 - mdpi.com
In recent years, significant changes have occurred in metastatic hormone-sensitive prostate
cancer (mHSPC) management, where docetaxel and new androgen receptor pathway …

[PDF][PDF] Management of systemic prostate cancer: current algorithm from castration sensitive to castration resistant setting.

C D'ANIELLO, C Cavaliere, C Foglia… - European Review for …, 2022 - europeanreview.org
In recent years, the advanced knowledge of clinical, biological and molecular features of
prostate cancer have led to the introduction of new drugs and have allowed the relocation of …

Bone health management in the continuum of prostate cancer disease

E Boopathi, R Birbe, SA Shoyele, RB Den… - Cancers, 2022 - mdpi.com
Simple Summary In this review, we summarize the risk factors of prostate cancer (PCa),
mechanism of PCa induced bone metastasis, current treatments for PCa induced bone …

Multi-institutional analysis of the clinical and genomic characteristics of black patients with metastatic hormone-sensitive prostate cancer

MN Freeman, A Jang, J Zhu, F Sanati… - The …, 2022 - academic.oup.com
Background The outcomes of metastatic hormone-sensitive prostate cancer (mHSPC) have
significantly improved through treatment intensification, yet Black representation in those …

Presence of CD133‐positive circulating tumor cells predicts worse progression‐free survival in patients with metastatic castration‐sensitive prostate cancer

Y Yang, Z Liu, Q Wang, K Chang… - … Journal of Urology, 2022 - Wiley Online Library
Objective To investigate the clinical significance of the expression of the stemness marker
CD133 in circulating tumor cells of newly diagnosed metastatic castration‐sensitive prostate …

Useful predictors of progression‐free survival for Japanese patients with LATITUDE‐high‐risk metastatic castration‐sensitive prostate cancer who received upfront …

K Takahara, T Naiki, T Ito, K Nakane… - … Journal of Urology, 2022 - Wiley Online Library
Objective Recently, hormonal therapy using abiraterone acetate, a second‐generation
androgen receptor axis‐targeted agent, was reported to improve overall survival and …

Transcriptional profile associated with clinical outcomes in metastatic hormone-sensitive prostate cancer treated with androgen deprivation and docetaxel

N Jiménez, Ò Reig, M Marín-Aguilera, C Aversa… - Cancers, 2022 - mdpi.com
Simple Summary The combination of androgen deprivation therapy (ADT) with docetaxel
(DX) or/and with novel anti-androgen receptor therapies have become standards for the …

Repeatability of 68Ga-PSMA-HBED-CC PET/CT–Derived Total Molecular Tumor Volume

R Seifert, P Sandach, D Kersting… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Molecular tumor volume (MTV) is a parameter of interest in prostate cancer for assessing
total disease burden on prostate-specific membrane antigen (PSMA) PET. Although …

Circular RNAs and drug resistance in genitourinary cancers: A literature review

G Long, S Ma, R Shi, Y Sun, Z Hu, K Chen - Cancers, 2022 - mdpi.com
Simple Summary Drug resistance to systematic treatment in genitourinary tumors severely
aggravated the burden on patients and society. Multiple mechanisms were involved in drug …

Conventional androgen deprivation therapy is associated with an increased risk of cardiovascular disease in advanced prostate cancer, a nationwide population …

JR Li, SS Wang, CS Chen, CL Cheng, SC Hung… - Plos one, 2022 - journals.plos.org
Purpose Androgen Deprivation Therapy (ADT) is the mainstay treatment in advanced
prostate cancer. We conducted a nationwide population-based study to evaluate the …