The global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
requires effective therapies against coronavirus disease 2019 (COVID-19), and neutralizing …

Background Two doses of mRNA vaccination have shown> 94% efficacy at preventing
COVID-19 mostly in naïve adults, but it is not clear if the second dose is needed to maximize …

Summary mRNA-1273 vaccine efficacy against SARS-CoV-2 Delta wanes over time;
however, there are limited data on the impact of durability of immune responses on …

Background Reinfection after primary SARS-CoV-2 infection is uncommon in adults, but little
is known about the risks, characteristics, severity, or outcomes of reinfection in children. We …

Abstract SARS-CoV-2, a newly emerging coronavirus that caused the COVID-19 epidemic,
has been spreading quickly throughout the world. Despite immunization and some fairly …

The COVID-19 pandemic has had a significant global impact, with more than 280,000,000
people infected and 5,400,000 deaths. The use of personal protective equipment and the …

Host genetic and environmental factors including age, biological sex, diet, geographical
location, microbiome composition and metabolites converge to influence innate and …

SARS-CoV-2 Omicron is highly transmissible and has substantial resistance to antibody
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …

Due to differences in human and murine angiotensin converting enzyme 2 (ACE-2) receptor,
initially available SARS-CoV-2 isolates could not infect mice. Here we show that serial …

Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), poses an imminent threat to our lives. Although …