Temporal lineage replacements and dominance of imported variants of concern during the COVID-19 pandemic in Kenya
G Kimita, J Nyataya, E Omuseni, F Sigei… - Communications …, 2022 - nature.com
Background Kenya's COVID-19 epidemic was seeded early in March 2020 and did not peak
until early August 2020 (wave 1), late-November 2020 (wave 2), mid-April 2021 (wave 3) …
until early August 2020 (wave 1), late-November 2020 (wave 2), mid-April 2021 (wave 3) …
Variant-specific vaccination induces systems immune responses and potent in vivo protection against SARS-CoV-2
Lipid nanoparticle (LNP)-mRNA vaccines offer protection against COVID-19; however,
multiple variant lineages caused widespread breakthrough infections. Here, we generate …
multiple variant lineages caused widespread breakthrough infections. Here, we generate …
[HTML][HTML] Spectrum of neuroimaging mimics in children with COVID-19 infection
AMC Wong, CH Toh - Biomedical Journal, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has affected over
200 million people globally (including over 30 million people in the United States), with …
200 million people globally (including over 30 million people in the United States), with …
[HTML][HTML] Identification of potential COVID-19 treatment compounds which inhibit SARS Cov2 prototypic, Delta and Omicron variant infection
P Kumar, M Mathayan, SP Smieszek, BP Przychodzen… - Virology, 2022 - Elsevier
Recurrent waves of COVID19 remain a major global health concern. Repurposing either
FDA-approved or clinically advanced drug candidates can save time and effort required for …
FDA-approved or clinically advanced drug candidates can save time and effort required for …
[HTML][HTML] Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA
virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the …
virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the …
Type of mRNA COVID-19 vaccine and immunomodulatory treatment influence humoral immunogenicity in patients with inflammatory rheumatic diseases
Patients with inflammatory rheumatic diseases (IRD) are at increased risk for worse COVID-
19 outcomes. Identifying whether mRNA vaccines differ in immunogenicity and examining …
19 outcomes. Identifying whether mRNA vaccines differ in immunogenicity and examining …
Syndecan-4 is a key facilitator of the SARS-CoV-2 delta variant's superior transmission
Emerging SARS-CoV-2 variants pose threats to vaccination campaigns against COVID-19.
Being more transmissible than the original virus, the SARS-CoV-2 B. 1.617 lineage, named …
Being more transmissible than the original virus, the SARS-CoV-2 B. 1.617 lineage, named …
COVID-19 patient serum less potently inhibits ACE2-RBD binding for various SARS-CoV-2 RBD mutants
D Junker, A Dulovic, M Becker, TR Wagner… - Scientific Reports, 2022 - nature.com
As global vaccination campaigns against SARS-CoV-2 proceed, there is particular interest
in the longevity of immune protection, especially with regard to increasingly infectious virus …
in the longevity of immune protection, especially with regard to increasingly infectious virus …
In silico genome analysis reveals the evolution and potential impact of SARS-CoV-2 Omicron structural changes on host immune evasion and antiviral therapeutics
D Chauhan, N Chakravarty, AV Jeyachandran… - Viruses, 2022 - mdpi.com
New variants of SARS-CoV-2 continue to evolve. The novel SARS-CoV-2 variant of concern
(VOC) B. 1.1. 529 (Omicron) was particularly menacing due to the presence of numerous …
(VOC) B. 1.1. 529 (Omicron) was particularly menacing due to the presence of numerous …
Computation of antigenicity predicts SARS-CoV-2 vaccine breakthrough variants
It has been reported that multiple severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants of concern (VOCs) including Alpha, Beta, Gamma, and Delta can reduce …
CoV-2) variants of concern (VOCs) including Alpha, Beta, Gamma, and Delta can reduce …