Patients with Marfan syndrome (MFS) develop thoracic aortic aneurysms as the aorta
presents excessive elastin breaks, fibrosis, and vascular smooth muscle cell (vSMC) death …

Aims The role of cardiopulmonary exercise testing (CPET) in predicting major adverse
cardiovascular events (MACE) in people with congenital heart disease (ConHD) is …

The pulmonary valve (PV) is the least imaged among the heart valves. However, pulmonary
regurgitation (PR) and pulmonary stenosis (PS) can occur in a variety of patients ranging …

The cardiovascular phenotype associated with RASopathies has expanded far beyond the
original descriptions of pulmonary valve stenosis by Dr Jaqueline Noonan in 1968 and …

The optimal course of intervention for patients with coexisting coarctation of the aorta (COA)
and mixed valvular disease (combinations of aortic and mitral valve pathologies, MVD) is an …

Objective To bring together patients, parents, charities and clinicians in a Priority Setting
Partnership to establish national clinical priorities for research in children and adults with …

Since its first description in 1971, the Fontan procedure and its modifications have led to a
substantial improvement in the survival rates of patients with a variety of types of complex …

Abstract The True Infection Rate (TIR) in the whole population of each country and the
Infection Fatality Rate (IFR) for coronavirus disease 2019 (COVID-19) are unknown although …

Congenital heart disease (CHD) is an indication which spans multiple specialties across
various genetic counseling practices. This practice resource aims to provide guidance on …

Background: Smaller studies have reported a higher offspring risk of congenital heart
defects (CHDs) for mothers with CHDs than for fathers with CHDs. In a large population …