Introduction Patients with a Fontan circulation are at risk for sequelae of Fontan physiology
during follow-up. Fontan physiology affects all organ systems and an overview of end-organ …

Transthoracic echocardiography is an essential tool in the diagnosis, assessment, and
management of paediatric and adult populations with suspected or confirmed congenital …

Thoracic aortic dilatation is a progressive condition that results from aging and many
pathological conditions (ie, connective tissue, inflammatory, shear stress disorders, severe …

In congenitally corrected transposition of the great arteries, the morphological right ventricle
supports the systemic circulation. This chronic exposure to pressure overload ultimately …

The field of congenital interventional cardiology has experienced tremendous growth in
recent years. Beginning with the development of early devices for transcatheter closure of …

Cells in the tissues and organs of a living body are subjected to mechanical forces, such as
pressure, friction, and tension from their surrounding environment. Cells are equipped with a …

Background The epidemiology of pulmonary hypertension (PH) in patients with adult
congenital heart disease in Western countries is already known. We investigate clinical …

Background The objective of this international multicenter study was to investigate both early
and late outcomes of cardiac resynchronization therapy (CRT) in patients with a systemic …

Background Although pregnancy outcomes in women with normally functioning
bioprosthetic valves (BPVs) are often good, structural valve dysfunction (SVD) may …

Modern medicine has undergone immense transformation in the past decade with the
discovery, innovation, and development of novel health systems and advanced patient care …