Surviving breast cancer cells post chemotherapy, metastasize, and develop recurrent tumors
at distant organs. These cells are known to exhibit a dormant phenotype at metastatic sites …

Objective Human eccrine sweat glands (eSG) represent vital components of the skin
involved in regulating body temperature. Especially the eccrine duct, which opens directly …

Histone deacetylase (HDAC) inhibitors are novel chemotherapy agents with potential utility
in the treatment of neuroblastoma, the most frequent solid tumor of childhood. Previous …

Novel approaches in 3D live cell microscopy - IOPscience This site uses cookies. By continuing
to use this site you agree to our use of cookies. To find out more, see our Privacy and Cookies …

Background Previous studies showed that proline-rich polypeptide (PRP-1) is a ligand for
innate immunity toll-like receptors (TLR), and an inhibitor of the mammalian target of …

Several biological processes related to cancer malignancy are regulated by 17-β estradiol
(E2) in ER+-breast cancer. To establish the role of E2 on the atypical cancer energy …

Cells attached to a substrate and grown in a two dimensional (2D) or suspension culture
cannot accurately replicate intercellular interactions in tissues and organs. Spheroids, being …

Anti-cancer drugs have the lowest success rate of approval in drug development programs.
Thus, preclinical assays that closely predict the clinical responses to drugs are of utmost …

Advancement in lab-on-a-chip (LOC) and microfluidics technologies has led to the
development of microscale cell culture platforms leading to physiological organ biomimetic …

Cutaneous Squamous Cell Carcinoma (cSCC) represents the second most common type of
skin cancer, which incidence is continuously increasing worldwide. Given its high frequency …