Systematic analysis of drug-associated myocarditis reported in the World Health Organization pharmacovigilance database

LS Nguyen, LT Cooper, M Kerneis… - Nature …, 2022 - nature.com
While multiple pharmacological drugs have been associated with myocarditis, temporal
trends and overall mortality have not been reported. Here we report the spectrum and main …

Divergent decennial trends in mental health according to age reveal poorer mental health for young people: repeated cross-sectional population-based surveys from …

S Krokstad, DA Weiss, MA Krokstad, V Rangul… - BMJ open, 2022 - bmjopen.bmj.com
Objectives Public health trends are formed by political, economic, historical and cultural
factors in society. The aim of this paper was to describe overall changes in mental health …

Ketamine activates adult-born immature granule neurons to rapidly alleviate depression-like behaviors in mice

R Rawat, E Tunc-Ozcan, TL McGuire, CY Peng… - Nature …, 2022 - nature.com
Ketamine treatment decreases depressive symptoms within hours, but the mechanisms
mediating these rapid antidepressant effects are unclear. Here, we demonstrate that activity …

[HTML][HTML] Myocarditis and pericarditis: case definition and guidelines for data collection, analysis, and presentation of immunization safety data

SKS Tejtel, FM Munoz, I Al-Ammouri, F Savorgnan… - Vaccine, 2022 - Elsevier
Myocarditis and/or pericarditis (also known as myopericarditis) are inflammatory diseases
involving the myocardium (with non-ischemic myocyte necrosis) and/or the pericardial sac …

Effect of diet and exercise on knee pain in patients with osteoarthritis and overweight or obesity: a randomized clinical trial

SP Messier, DP Beavers, K Queen, SL Mihalko… - Jama, 2022 - jamanetwork.com
Importance Some weight loss and exercise programs that have been successful in
academic center–based trials have not been evaluated in community settings. Objective To …

Oxygen-ozone therapy for reducing pro-inflammatory cytokines serum levels in musculoskeletal and temporomandibular disorders: a comprehensive review

A de Sire, N Marotta, M Ferrillo, F Agostini… - International journal of …, 2022 - mdpi.com
To date, the application of oxygen-ozone (O2O3) therapy has significantly increased in the
common clinical practice in several pathological conditions. However, beyond the favorable …

Single-cell RNA-seq analysis of cells from degenerating and non-degenerating intervertebral discs from the same individual reveals new biomarkers for intervertebral …

H Cherif, M Mannarino, AS Pacis, J Ragoussis… - International journal of …, 2022 - mdpi.com
In this study, we used single-cell transcriptomic analysis to identify new specific biomarkers
for nucleus pulposus (NP) and inner annulus fibrosis (iAF) cells, and to define cell …

Gut-derived systemic inflammation as a driver of depression in chronic liver disease

VT Kronsten, TH Tranah, C Pariante… - Journal of hepatology, 2022 - Elsevier
Depression and chronic liver disease (CLD) are important causes of disability, morbidity and
mortality worldwide and their prevalence continues to rise. The rate of depression in CLD is …

[HTML][HTML] Use of mobile and wearable artificial intelligence in child and adolescent psychiatry: scoping review

V Welch, TJ Wy, A Ligezka, LC Hassett… - Journal of medical …, 2022 - jmir.org
Background Mental health disorders are a leading cause of medical disabilities across an
individual's lifespan. This burden is particularly substantial in children and adolescents …

The microbiota–gut–brain axis in depression: The potential pathophysiological mechanisms and microbiota combined antidepression effect

F Zhu, H Tu, T Chen - Nutrients, 2022 - mdpi.com
Depression is a kind of worldwide mental illness with the highest morbidity and disability
rate, which is often accompanied by gastrointestinal symptoms. Experiments have …