Psychiatric disorders are one of the leading causes of disability worldwide and affect the
quality of life of both individuals and the society. The current understanding of these …

Background Thrombo-inflammation is an important checkpoint that orchestrates infarct
development in ischemic stroke. However, the underlying mechanism remains largely …

Background Summary measures such as disability-adjusted life years (DALY) are becoming
increasingly important for the standardized assessment of the burden of disease due to …

The progression of intervertebral disc degeneration (IDD) is characterized by an initial
chronic local inflammatory response and ultimately leads to unbalanced anabolic/catabolic …

Background To study differences in oxidative stress markers and antioxidants among
patients with bipolar depression (BPD) and unipolar depression (UPD). Methods Data …

Objective To evaluate if gait biomechanics are associated with increased risk of structurally
diagnosed disease onset or progression of lower limb osteoarthritis (OA). Method A …

Pain chronicity involves unpleasant experience in both somatosensory and affective
aspects, accompanied with the prefrontal cortex (PFC) neuroplastic alterations. However …

Chronic pelvic pain (CPP) causes important negative effects on quality of life. Endometriosis
is the most common cause of CPP in females, and diagnostic delay is over six years …

The World Health Organization (WHO) recently published guidelines on the implementation
of a new Integrated Care for Older People (ICOPE) framework in 2017–2019. It is an …

Sickle cell disease and its variants constitute the most common inherited blood disorders
affecting millions of individuals worldwide. Significant information regarding the nature of the …