MyoG-enhanced circGPD2 regulates chicken skeletal muscle development by targeting miR-203a

X Shen, C Cui, S Tang, S Han, Y Zhang, L Xia… - International Journal of …, 2022 - Elsevier
Circular RNAs (circRNAs) are a subclass of RNA macromolecules that are reported to be
involved in the regulation of skeletal muscle development. However, the functions and …

Linc00312 single nucleotide polymorphism as biomarker for chemoradiotherapy induced hematotoxicity in nasopharyngeal carcinoma patients

Z Guo, YJ Wang, BS He, J Zhou - Disease Markers, 2022 - Wiley Online Library
Background. Linc00312 is downregulated in nasopharyngeal carcinoma (NPC) and
associates with poor treatment efficacy. Genetic variations are the main cause of individual …

LINC00624/TEX10/NF-κB axis promotes proliferation and migration of human prostate cancer cells

J Zhou, J Li, C Qian, F Qiu, Q Shen, R Tong… - Biochemical and …, 2022 - Elsevier
Prostate cancer (PCa) is a malignant epithelial tumor with a high rate of biochemical or local
recurrence. Studies have suggested that LINC00624 plays an important oncogenic role in …

[HTML][HTML] Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG

N Giannareas, Q Zhang, X Yang, R Na, Y Tian… - Nature …, 2022 - nature.com
Genome-wide association studies have identified 270 loci conferring risk for prostate cancer
(PCa), yet the underlying biology and clinical impact remain to be investigated. Here we …

[HTML][HTML] Androgen receptor-mediated transcription in prostate cancer

D Özturan, T Morova, NA Lack - Cells, 2022 - mdpi.com
Androgen receptor (AR)-mediated transcription is critical in almost all stages of prostate
cancer (PCa) growth and differentiation. This process involves a complex interplay of …

[HTML][HTML] An enhancer variant at 16q22.1 predisposes to hepatocellular carcinoma via regulating PRMT7 expression

T Shen, T Ni, J Chen, H Chen, X Ma, G Cao… - Nature …, 2022 - nature.com
Most cancer causal variants are found in gene regulatory elements, eg., enhancers.
However, enhancer variants predisposing to hepatocellular carcinoma (HCC) remain …

PCAT19 regulates the proliferation and apoptosis of lung cancer cells by inhibiting miR‐25‐3p via targeting the MAP2K4 signal Axis

B Wang, S Yang, Y Jia, J Yang, K Du, Y Luo… - Disease …, 2022 - Wiley Online Library
Both PCAT19 and miR‐25‐3p have been reported in lung cancer studies, but whether there
is a correlation between the two and whether they jointly regulate the progress of lung …

Prostate Cancer transcriptomic regulation by the interplay of germline risk alleles, somatic mutations, and 3D genomic architecture

J Yuan, KE Houlahan, SG Ramanand, S Lee, GH Baek… - Cancer discovery, 2022 - AACR
Prostate cancer is one of the most heritable human cancers. Genome-wide association
studies have identified at least 185 prostate cancer germline risk alleles, most noncoding …

[HTML][HTML] LncRNA PCAT19 induced by SP1 and acted as oncogene in gastric cancer competitively binding to miR429 and upregulating DHX9

L Xiao, W Yuan, C Huang, Q Luo, R Xiao… - Journal of …, 2022 - ncbi.nlm.nih.gov
Increasing evidence suggests that long non-coding RNAs (lncRNAs) are crucial in cancer
biological processes. To investigate if lncRNA contributes to gastric cancer (GC), we …

Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression

Y Li, C Ma, S Li, J Wang, W Li, Y Yang, X Li… - Advanced …, 2022 - Wiley Online Library
Genome‐wide association studies have identified 3p21. 1 as a robust risk locus for
schizophrenia. However, the underlying molecular mechanisms remain elusive. Here a …