Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease
HPS3/TIMI55-REVEAL Collaborative … - European Heart …, 2022 - academic.oup.com
Aims REVEAL was the first randomized controlled trial to demonstrate that adding
cholesteryl ester transfer protein inhibitor therapy to intensive statin therapy reduced the risk …
cholesteryl ester transfer protein inhibitor therapy to intensive statin therapy reduced the risk …
[HTML][HTML] Medicinal and edible plants in the treatment of dyslipidemia: advances and prospects
Y Hu, X Chen, M Hu, D Zhang, S Yuan, P Li, L Feng - Chinese Medicine, 2022 - Springer
Dyslipidemia is an independent risk factor of cardiovascular diseases (CVDs), which lead to
the high mortality, disability, and medical expenses in the worldwide. Based on the previous …
the high mortality, disability, and medical expenses in the worldwide. Based on the previous …
[HTML][HTML] Statins and cognition: Modifying factors and possible underlying mechanisms
T Jamshidnejad-Tosaramandani… - Frontiers in Aging …, 2022 - frontiersin.org
Statins are a class of widely prescribed drugs used to reduce low-density lipoprotein
cholesterol (LDL-C) and important to prevent cardiovascular diseases (CVD). Most statin …
cholesterol (LDL-C) and important to prevent cardiovascular diseases (CVD). Most statin …
Statin associated muscle symptoms: An update and review
Statin therapy has been shown to have a significant effect on lowering of low-density
lipoprotien cholesterol (LDL-C) levels. This subsequently results in cardiovascular (CV) …
lipoprotien cholesterol (LDL-C) levels. This subsequently results in cardiovascular (CV) …
[HTML][HTML] Statins and prostate cancer—hype or hope? The epidemiological perspective
EL Craig, KH Stopsack, E Evergren, LZ Penn… - Prostate cancer and …, 2022 - nature.com
Background Men using cholesterol-lowering statin medications have been found to have
lower risks of both advanced and fatal prostate cancer in multiple registry-based studies and …
lower risks of both advanced and fatal prostate cancer in multiple registry-based studies and …
Integrating a polygenic risk score for coronary artery disease as a risk‐enhancing factor in the pooled cohort equation: a cost‐effectiveness analysis study
D Mujwara, G Henno, ST Vernon, S Peng… - Journal of the …, 2022 - Am Heart Assoc
Background Cardiovascular diseases are the leading cause of death in the United States,
yet a significant proportion of adults at high risk remain undetected by standard screening …
yet a significant proportion of adults at high risk remain undetected by standard screening …
Intensity of and adherence to lipid‐lowering therapy as predictors of major adverse cardiovascular outcomes in patients with coronary heart disease
Background The effectiveness of lipid‐lowering therapy (LLT) is affected by both intensity
and adherence. This study evaluated the associations of LLT intensity, adherence, and the …
and adherence. This study evaluated the associations of LLT intensity, adherence, and the …
Inflammation in coronary atherosclerosis and its therapeutic implications
NJ Montarello, MT Nguyen, DTL Wong… - … drugs and therapy, 2022 - Springer
Atherosclerotic coronary artery disease has a complex pathogenesis which extends beyond
cholesterol intimal infiltration. It involves chronic inflammation of the coronary artery wall …
cholesterol intimal infiltration. It involves chronic inflammation of the coronary artery wall …
The role of pharmacogenomics in contemporary cardiovascular therapy: a position statement from the European Society of Cardiology Working Group on …
EF Magavern, JC Kaski, RM Turner… - European Heart …, 2022 - academic.oup.com
There is a strong and ever-growing body of evidence regarding the use of
pharmacogenomics to inform cardiovascular pharmacology. However, there is no common …
pharmacogenomics to inform cardiovascular pharmacology. However, there is no common …
Net benefit, calibration, threshold selection, and training objectives for algorithmic fairness in healthcare
A growing body of work uses the paradigm of algorithmic fairness to frame the development
of techniques to anticipate and proactively mitigate the introduction or exacerbation of health …
of techniques to anticipate and proactively mitigate the introduction or exacerbation of health …