Lipid-lowering drug therapy: critical approach for implementation in clinical practice
M Rossi, E Fabris, D Barbisan, L Massa… - American Journal of …, 2022 - Springer
Increased levels of low-density lipoprotein cholesterol (LDL-C) are recognized as a primary
risk factor for atherosclerotic cardiovascular disease, which remains the leading cause of …
risk factor for atherosclerotic cardiovascular disease, which remains the leading cause of …
Metabolite signature of simvastatin treatment involves multiple metabolic pathways
L Fernandes Silva, R Ravi, J Vangipurapu, M Laakso - Metabolites, 2022 - mdpi.com
Statins inhibit the 3-hydroxy-3-methylglutaryl-CoA reductase enzyme and are the most
widely used medication for hypercholesterolemia. Previous studies on the metabolite …
widely used medication for hypercholesterolemia. Previous studies on the metabolite …
Efficacy and safety of PCSK9 monoclonal antibodies in patients with Diabetes
Purpose Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are novel drugs
that have proven efficacy in improving cardiovascular outcomes. Roles for the PCSK9 …
that have proven efficacy in improving cardiovascular outcomes. Roles for the PCSK9 …
Cardiovascular events in adult polymyositis and dermatomyositis: a meta-analysis of observational studies
A Xiong, Z Hu, S Zhou, Y Qiang, Z Song, H Chen… - …, 2022 - academic.oup.com
Objectives We aimed to review whether PM and DM patients have an increased
cardiovascular (CV) risk, including ischaemic heart disease (IHD), cerebrovascular …
cardiovascular (CV) risk, including ischaemic heart disease (IHD), cerebrovascular …
A review of statin intolerance: a focus on statin-attributed muscle symptoms
CE Orringer, JK Grant, L Tokgozoglu - Current atherosclerosis reports, 2022 - Springer
Abstract Purpose of Review To provide a systematic approach to management of the patient
with statin-attributed muscle symptoms. Recent Findings We examined the prevalence of …
with statin-attributed muscle symptoms. Recent Findings We examined the prevalence of …
Proprotein convertase subtilisin/kexin type 9 inhibition after acute coronary syndrome or prior myocardial infarction
GG Schwartz, RP Giugliano - Current Opinion in Lipidology, 2022 - journals.lww.com
Proprotein convertase subtilisin/kexin type 9 inhibition aft... : Current Opinion in Lipidology
Proprotein convertase subtilisin/kexin type 9 inhibition after acute coronary syndrome or prior …
Proprotein convertase subtilisin/kexin type 9 inhibition after acute coronary syndrome or prior …
The role of inflammation as a preponderant risk factor in cardiovascular diseases
RD García, JA Asensio, DJ Perdicaro… - Current Vascular …, 2022 - ingentaconnect.com
Cardiovascular diseases cause considerable health and economic burden, as they are the
leading cause of disability and death in the western world. Inactivity, hypertension, obesity …
leading cause of disability and death in the western world. Inactivity, hypertension, obesity …
Aspirin for primary stroke prevention; evidence for a differential effect in men and women
Z Gdovinova, C Kremer, S Lorenzano… - Frontiers in …, 2022 - frontiersin.org
Background: The use of aspirin for primary prevention of cardiovascular events in men and
women remains controversial. Our study aimed to investigate the role of aspirin in primary …
women remains controversial. Our study aimed to investigate the role of aspirin in primary …
Lifetime cardiovascular disease risk by coronary artery calcium score in individuals with and without diabetes: an analysis from the multi-ethnic study of …
BS Ferket, MGM Hunink, U Masharani, W Max… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE To assess lifetime cardiovascular disease (CVD) risk by coronary artery calcium
(CAC) score in individuals with diabetes from the Multi-Ethnic Study of Atherosclerosis …
(CAC) score in individuals with diabetes from the Multi-Ethnic Study of Atherosclerosis …
Statin therapy for the primary prevention of cardiovascular disease: Cons
V Durai, RF Redberg - Atherosclerosis, 2022 - Elsevier
While recent decades have seen substantial reductions in cardiovascular mortality, heart
disease remains the number one cause of death both in the United States and globally. This …
disease remains the number one cause of death both in the United States and globally. This …