Peptides cancer vaccines are designed based on the epitope peptides that can elicit
humoral and cellular immune responses targeting tumor‐associated antigens (TAAs) or …

Effective activation of cGAS-STING pathway combined with immune checkpoint blockade
(ICB) within the immunosuppressive tumor microenvironment to induce stronger immune …

The MYC transcription factor, encoded by the c‐MYC proto‐oncogene, is activated by
growth‐promoting signals, and is a key regulator of biosynthetic and metabolic pathways …

Response to immunotherapies can be variable and unpredictable. Pathology-based
phenotyping of tumors into 'hot'and 'cold'is static, relying solely on T-cell infiltration in single …

Simple Summary Bladder cancer is the ninth most common cancer worldwide. Immune
checkpoint inhibitors, a novel class of immunotherapy drugs that restore natural antitumoral …

Background The phase 3 CheckMate 214 trial demonstrated higher response rates and
improved overall survival with nivolumab plus ipilimumab versus sunitinib in first-line …

Cancer immunotherapy has achieved remarkable success over the past decade by
modulating patients' own immune systems and unleashing pre-existing immunity. However …

Simple Summary The biomedical application of metal–organic frameworks in cancer
theranostics has become a research hotspot with rapid progress. As a typical representative …

Purpose: Combinations of immune-checkpoint inhibitors (ICI) with other cancer therapies
have been approved for advanced cancers in multiple indications, and numerous trials are …

Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor,
human epidermal growth factor receptor 2 and progesterone receptor negative. TNBC is …