Human lens epithelial cells, due to their ocular function, are normally exposed to radiating
and oxidative stress conditions. Indeed, the lens is an environment rich in endogenous …

Fatty acids (FAs) have been shown to exhibit a pro-inflammatory response in various cell
types, but astrocytes have been mostly overlooked. FAs, both saturated and unsaturated …

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection [1],[2]. Excessive production of response immune leads to widespread tissue …

Objective: TIGIT/CD155 has attracted widespread attention as a new immune checkpoint
and a potential target for cancer immunotherapy. In our study, we evaluated the role of …

NF-κB is an important transcription regulator that has an essential role in gene expression
during different biological processes, starting from embryonic developmental processes …

By the year 2035 more than 4 billion people might be affected by obesity and being
overweight. Adipocyte-derived Extracellular Vesicles (ADEVs/ADEV-singular) are essential …

Helicobacter pylori has been described to activate the non-canonical NF-κB pathway in a
secondary loop. However, the role of this pathway in gastric carcinogenesis remains …

African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious
and fatal disease found in swine. However, the viral proteins and mechanisms responsible …