In the endoplasmic reticulum (ER), the translocation-associated protein complex (TRAP),
also called signal sequence receptor (SSR), includes four integral membrane proteins …

Introduction Pancreatic and duodenal homeobox factor-1 (PDX-1) is an imperative gene for
insulin secretion in maturity-onset diabetes of the young 4. PDX-1 gene polymorphism was …

Abstract Background Coronary Heart Disease (CHD) is the leading cause of death in
industrialized countries. There is currently no direct relation between CHD and type 2 …

Abstract Type 2 diabetes (T2D) is caused by genetic and environmental factors as well as
gene‐environment interactions. However, these interactions have not been systematically …

The amount of biomedical data collected and stored has grown significantly. Analyzing
these extensive amounts of data cannot be done by individuals or single organizations …

Aim Several studies have identified associations between type 2 diabetes (T2D) and DNA
methylation (DNAm). However, the causal role of these associations remains unclear. This …

To assess the burden of type 2 diabetes (T2D) and its genetic profile in endogamous
populations of India given the paucity of data, we aimed to determine the prevalence of T2D …

Common complex diseases are among the top leading causes of death globally. Due to
their heavy burden on the healthcare systems and on affected individuals themselves …

An increasing pandemic of obesity and diabetes (diabetes mellitus, DM) has become a
serious health concern worldwide because these diseases contribute to the development of …

Diabetes, as one of the major diseases in industrial countries, affects over 350 million
people worldwide. Type 1 (T1D) and type 2 diabetes (T2D) are the most common forms. T2D …