Reshaping sensory representations by task-specific brain states: Toward cortical circuit mechanisms

N Zhang, N Xu - Current Opinion in Neurobiology, 2022 - Elsevier
Perception is internally constructed by integrating brain states with external sensory inputs, a
process depending on the topdown modulation of sensory representations. A wealth of …

Activation of basal forebrain-to-lateral habenula circuitry drives reflexive aversion and suppresses feeding behavior

JL Swanson, J Ortiz-Guzman, S Srivastava, PS Chin… - Scientific Reports, 2022 - nature.com
Environmental cues and internal states such as mood, reward, or aversion directly influence
feeding behaviors beyond homeostatic necessity. The hypothalamus has been extensively …

Optic flow processing

HG Krapp - Encyclopedia of computational neuroscience, 2022 - Springer
A system of differential equations simulating the part of the brain that is responsible for the
control of ocular movements. Each equation describes the evolution of the output of one unit …

[HTML][HTML] How general anesthetics work: from the perspective of reorganized connections within the brain

TJ Shin, PJ Kim, B Choi - Korean journal of anesthesiology, 2022 - synapse.koreamed.org
General anesthesia is critical for various procedures and surgeries. Despite the widespread
use of anesthetics, their precise mechanisms remain poorly understood. Anesthetics …

Attentional modulation is orthogonal to disinhibition by VIP interneurons in primary visual cortex

D Myers-Joseph, KA Wilmes, M Fernandez-Otero… - bioRxiv, 2022 - biorxiv.org
Attentional modulation of sensory processing is a key feature of cognition, yet its neural
circuit basis is poorly understood. A candidate mechanism is the disinhibition of pyramidal …

Serum unsaturated phosphatidylcholines predict longitudinal basal forebrain degeneration in Alzheimer's disease

HRC Shanks, KM Onuska, DK Barupal… - Brain …, 2022 - academic.oup.com
Basal forebrain cholinergic neurons are among the first cell types affected by Alzheimer's
disease pathology, but the cause of their early vulnerability is unknown. The lipid …

Vagus nerve stimulation recruits the central cholinergic system to enhance perceptual learning

KA Martin, ES Papadoyannis, JK Schiavo, SS Fadaei… - bioRxiv, 2022 - biorxiv.org
Perception can be refined by experience up to certain limits. It is unclear if perceptual
limitations are absolute or could be partially overcome via enhanced neuromodulation …

Network states classification based on local field potential recordings in the awake mouse neocortex

Y Zerlaut, S Zucca, T Fellin, S Panzeri - Eneuro, 2022 - eneuro.org
Recent studies using intracellular recordings in awake behaving mice revealed that cortical
network states, defined based on membrane potential features, modulate sensory …

Genetically tagging cholinergic diversity

JK Luo, L Pinto - Neuron, 2022 - cell.com
Genetically tagging cholinergic diversity: Neuron Skip to Main Content Advertisement Neuron
This journal offers authors two options (open access or subscription) to publish research Submit …

[HTML][HTML] A selective degeneration of cholinergic neurons mediated by NRADD in an Alzheimer's disease mouse model

L Li, B Zhang, X Tang, Q Yu, A He, Y Lu, X Li - Cell Insight, 2022 - Elsevier
Cholinergic neurons in the basal forebrain constitute a major source of cholinergic inputs to
the forebrain, modulate diverse functions including sensory processing, memory and …