Background Fatty acids are important dietary factors that have been extensively studied for
their implication in health and disease. Evidence from epidemiological studies and …

Background Despite early interest in the health effects of polyunsaturated fatty acids (PUFA),
there is still substantial controversy and uncertainty on the evidence linking PUFA to …

Cardiovascular disease (CVD) risk and rate of progression is determined by genetic,
environmental and behavioural factors. Majority of genotype–diet–CVD phenotype research …

Cardiovascular disease (CVD) arises as a result of genetic predisposition in the context of a
disease-promoting environment. While several risk factors have been identified for CVD …

The role of fatty acids (FAs) in primary prevention of coronary artery disease (CAD) is highly
debated, and the modification effect by genetic risk profiles remains unclear. Here, we report …

Aims/hypothesis Epidemiological data on the associations of circulating fatty acid levels with
type 2 diabetes are inconsistent. We conducted a two-sample Mendelian randomisation …

Genetic polymorphism in human populations is part of the evolutionary process that results
from the interaction between the environment and the human genome. Recent changes in …

The cardioprotective actions of the fish oil (FO)-derived long-chain n-3 polyunsaturated fatty
acids (LC n-3 PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have …

Background The causal relevance of polyunsaturated fatty acids (PUFAs) for risk of site-
specific cancers remains uncertain. Methods Using a Mendelian randomization (MR) …

Scope Tissue concentrations of omega‐3 fatty acids may reduce cardiovascular disease
risk, and genetic variants are associated with circulating fatty acids concentrations. Whether …