[HTML][HTML] SmDXS5, acting as a molecular valve, plays a key regulatory role in the primary and secondary metabolism of tanshinones in Salvia miltiorrhiza

D Zhang, L Luo, Z Wang, W Xu, J Li, S Tan… - Frontiers in Plant …, 2022 - frontiersin.org
Red sage, the dry root and rhizome of the herbaceous plant Salvia miltiorrhiza Bunge, is
widely used for treating various diseases. The low content of tanshinones (terpenoids) has …

[HTML][HTML] Transcription Factor SmWRKY1 Positively Promotes the Biosynthesis of Tanshinones in Salvia miltiorrhiza

W Cao, Y Wang, M Shi, X Hao, W Zhao… - Frontiers in Plant …, 2018 - frontiersin.org
Tanshinones, one group of bioactive diterpenes, were widely used in the treatment of
cardiovascular diseases. WRKYs play important roles in plant metabolism, but their …

[HTML][HTML] Transcriptomic analysis reveals potential genes involved in tanshinone biosynthesis in Salvia miltiorrhiza

Y Chang, M Wang, J Li, S Lu - Scientific reports, 2019 - nature.com
Tanshinones are important bioactive components in Salvia miltiorrhiza and mainly
accumulate in the periderms of mature roots. Tanshinone biosynthesis is a complicated …

Chromosome-level genome assembly of Salvia miltiorrhiza with orange roots uncovers the role of Sm2OGD3 in catalyzing 15,16-dehydrogenation of tanshinones

X Pan, Y Chang, C Li, X Qiu, X Cui, F Meng… - Horticulture …, 2023 - academic.oup.com
Salvia miltiorrhiza is well known for its clinical practice in treating heart and cardiovascular
diseases. Its roots, used for traditional Chinese medicine materials, are usually brick-red due …

[HTML][HTML] Comprehensive transcriptome profiling of Salvia miltiorrhiza for discovery of genes associated with the biosynthesis of tanshinones and phenolic acids

W Zhou, Q Huang, X Wu, Z Zhou, M Ding, M Shi… - Scientific Reports, 2017 - nature.com
Tanshinones and phenolic acids are crucial bioactive compounds biosynthesized in Salvia
miltiorrhiza. Methyl jasmonate (MeJA) is an effective elicitor to enhance the production of …

The SmMYB36-SmERF6/SmERF115 module regulates the biosynthesis of tanshinones and phenolic acids in salvia miltiorrhiza hairy roots

Q Li, X Fang, Y Zhao, R Cao, J Dong… - Horticulture …, 2023 - academic.oup.com
Tanshinone and phenolic acids are the most important active substances of Salvia
miltiorrhiza, and the insight into their transcriptional regulatory mechanisms is an essential …

[HTML][HTML] Overexpression of SmSCR1 Promotes Tanshinone Accumulation and Hairy Root Growth in Salvia miltiorrhiza

W Zhou, S Wang, Y Shen, Y Liu, I Maoz… - Frontiers in Plant …, 2022 - frontiersin.org
Lipid-soluble tanshinone is one of the main bioactive substances in the medicinal plant
Salvia miltiorrhiza, and its medicinal demand is growing rapidly. Yeast extract (YE) …

[HTML][HTML] SmMYC2b Enhances Tanshinone Accumulation in Salvia miltiorrhiza by Activating Pathway Genes and Promoting Lateral Root Development

Y Zhou, J Feng, Q Li, D Huang, X Chen, Z Du… - Frontiers in Plant …, 2020 - frontiersin.org
Salvia miltiorrhiza Bunge (Lamiaceae) is an economically important medicinal plant as well
as an emerging model plant. Our previous studies indicate that Sm MYC2b is a positive …

[HTML][HTML] Transcriptome Analysis of Medicinal Plant Salvia miltiorrhiza and Identification of Genes Related to Tanshinone Biosynthesis

L Yang, G Ding, H Lin, H Cheng, Y Kong, Y Wei… - PLoS …, 2013 - journals.plos.org
Salvia miltiorrhiza Bunge, a perennial plant of Lamiaceae, accumulates abietane-type
diterpenoids of tanshinones in root, which have been used as traditional Chinese medicine …

SmWD40-2 functions as a positive regulator of both tanshinones and phenolic acids biosynthesis in Salvia miltiorrhiza Bunge hairy roots

B Xing, J Sun, H Yu, X Zhang, K Fan, Z Liang - Industrial Crops and …, 2023 - Elsevier
Salvia miltiorrhiza Bunge, one of the most commonly used traditional Chinese medicine,
whose target bioactive compounds are tanshinones and phenolic acids. However, the …