The skin is the largest organ of the human body and prone to various diseases, including
cancer; thus, provides the first line of defense against exogenous biological and non …

Despite progress made with immune checkpoint inhibitors and targeted therapies, skin
cancer remains a significant public health concern in the United States. The intricacies of the …

The skin functions as a barrier between the organism and the surrounding environment.
Direct exposure to external stimuli and the accumulation of genetic mutations may lead to …

Simple Summary Non-melanoma skin cancer (NMSC) is the main type of cancer in the
Caucasian population, and the number of cases continues to rise. Research mostly focuses …

Understanding of cancer with the help of ever-expanding cutting edge technological tools
and bioinformatics is revolutionizing modern cancer research by broadening the space of …

Background Currently, molecularly targeted drugs are part of the therapeutic arsenal for the
treatment of many neoplasms and are responsible for improvements in the quality of life and …

Cancer drug discovery is currently dominated by clinical trials or clinical research. Several
potential drug candidates have been brought into the pipeline of drug discovery after …

Melanoma and non-melanoma cutaneous malignancies are some of the leading causes of
cancer-related death in the United States. Though melanoma is more known to have a high …

Human malignancies arise predominantly in tissues of epithelial origin, where the stepwise
transformation from healthy epithelium to premalignant dysplasia to invasive neoplasia …

The nuclear factor kappa B (NF‐κB) signalling pathway exhibits both tumour‐promoting and
tumour‐suppressing functions in different tissues and models of carcinogenesis. In particular …