[HTML][HTML] Effect of carotenoids on paraoxonase-1 activity and gene expression

A Otocka-Kmiecik - Nutrients, 2022 - mdpi.com
Paraoxonase 1 (PON1) is an antioxidant enzyme attached to HDL with an anti-atherogenic
potential. It protects LDL and HDL from lipid peroxidation. The enzyme is sensitive to various …

Effect of dietary lipids on paraoxonase-1 activity and gene expression

G Ferretti, T Bacchetti - Nutrition, Metabolism and Cardiovascular Diseases, 2012 - Elsevier
AIMS: Aim of the paper was to summarize the literature about the effect of dietary lipids on
activity of paraoxonase-1 (PON1), a multifunctional enzyme associated with high density …

Determinants of paraoxonase 1 status: genes, drugs and nutrition

C Schrader, G Rimbach - Current medicinal chemistry, 2011 - ingentaconnect.com
Paraoxonase 1 (PON1) is an enzyme which is mainly synthesized in the liver. PON1
circulates in the blood bound to HDL and delays or prevents the oxidation of LDL. Single …

Paraoxonase 1 Q192R (PON1-192) polymorphism is associated with reduced lipid peroxidation in healthy young men on a low-carotenoid diet supplemented with …

A Bub, SW Barth, B Watzl, K Briviba… - British journal of …, 2005 - cambridge.org
The HDL-bound enzyme paraoxonase (PON) protects LDL from oxidation and may therefore
attenuate the development of atherosclerosis. We examined the effect of tomato and carrot …

[HTML][HTML] Antioxidant and anti-inflammatory role of paraoxonase 1: implication in arteriosclerosis diseases

D Litvinov, H Mahini, M Garelnabi - North American journal of …, 2012 - ncbi.nlm.nih.gov
Abstract Paraoxonase 1 (PON1) is a hydrolytic enzyme with wide range of substrates, and
capability to protect against lipid oxidation. Despite of the large number of compounds that …

[HTML][HTML] Phytochemicals as modulators of paraoxonase-1 in health and diseases

ZN Arab, D Khayatan, SM Razavi, K Zare… - Antioxidants, 2022 - mdpi.com
Chronic diseases such as cardiovascular disease (CVD), atherosclerosis, chronic liver
disease, and neurodegenerative diseases are major causes of mortality. These diseases …

[HTML][HTML] The effects of anthocyanins and their microbial metabolites on the expression and enzyme activities of paraoxonase 1, an important marker of HDL function

HT Aboufarrag, PW Needs, G Rimbach, PA Kroon - Nutrients, 2019 - mdpi.com
High circulating HDL concentrations and measures of various HDL functions are inversely
associated with cardiovascular disease (CVD) risk. Paraoxonase 1 (PON1) contributes to …

The epigenetic regulation of paraoxonase 1 (PON1) as an important enzyme in HDL function: The missing link between environmental and genetic regulation

A Mahrooz, M Mackness, A Bagheri… - Clinical …, 2019 - Elsevier
Abstract Background Paraoxonase 1 (PON1) is an important antiatherogenic and
antioxidant enzyme in the circulation that has been associated with adverse health …

[HTML][HTML] Dietary modifications and gene polymorphisms alter serum paraoxonase activity in healthy women

M Rantala, ML Silaste, A Tuominen, YA Kesäniemi… - The Journal of …, 2002 - Elsevier
Paraoxonase-1 (PON1), a HDL-associated enzyme, may protect against the development of
atherosclerosis. Serum PON1 activity and PON1-mediated capacity of HDL to prevent …

Determinants of paraoxonase activity in healthy adults

C Boesch‐Saadatmandi, G Rimbach… - Molecular nutrition & …, 2010 - Wiley Online Library
Abstract Scope: Paraoxonase‐1 (PON‐1), associated with HDL, is regarded as anti‐
atherogenic, attributed to its ability to hydrolyze oxidized lipids. Here, the impact of PON and …