Importance Very preterm neonates (24-32 weeks' gestation) remain at a higher risk of
morbidity and neurodevelopmental adversity throughout their lifespan. Because the extent of …

Epigenetic age acceleration is a risk factor for chronic diseases of ageing and may reflect
aspects of biological ageing. However, few studies have examined epigenetic ageing during …

ContextNeonatal infections are frequent complications of extremely low-birth-weight (ELBW)
infants receiving intensive care. ObjectiveTo determine if neonatal infections in ELBW …

The development of biological markers of aging has primarily focused on adult samples.
Epigenetic clocks are a promising tool for measuring biological age that show impressive …

METHODS: Buccal cells were collected from 45 ELBW survivors and 49 NBW control
participants at 30 to 35 years of age. Epigenetic age was calculated from the weighted …

Background Studies reporting accelerated ageing in children with affective disorders or
maltreatment exposure have relied on algorithms for estimating epigenetic age derived from …

Objectives To evaluate whether the number of postnatal infections is associated with
abnormal white matter maturation and poorer motor neurodevelopmental outcomes at 36 …

Background The fetal origins of mental health is a well-established framework that currently
lacks a robust index of the biological embedding of prenatal adversity. The Pediatric-Buccal …

Background Infants born very preterm are more likely to experience neonatal morbidities
compared to their term peers. Variations in DNA methylation (DNAm) associated with these …

Objectives To document associations between confirmed and suspected neonatal infection
and motor, cognitive, educational, and mental health outcomes of very preterm (VPT)-born …