A valence‐engineered self‐cascading antioxidant nanozyme for the therapy of inflammatory bowel disease
Q Wang, C Cheng, S Zhao, Q Liu, Y Zhang… - Angewandte …, 2022 - Wiley Online Library
Antioxidant treatment strategy by scavenging reactive oxygen species (ROS) is a highly
effective disease treatment option. Nanozymes with multiple antioxidant activities can cope …
effective disease treatment option. Nanozymes with multiple antioxidant activities can cope …
[HTML][HTML] ROS scavenging Mn 3 O 4 nanozymes for in vivo anti-inflammation
Reactive oxygen species (ROS)-induced oxidative stress is linked to various diseases,
including cardiovascular disease and cancer. Though highly efficient natural ROS …
including cardiovascular disease and cancer. Though highly efficient natural ROS …
A Redox Modulatory Mn3O4 Nanozyme with Multi‐Enzyme Activity Provides Efficient Cytoprotection to Human Cells in a Parkinson's Disease Model
Nanomaterials with enzyme‐like activities (nanozymes) attracts significant interest due to
their therapeutic potential for the treatment of various diseases. Herein, we report that a …
their therapeutic potential for the treatment of various diseases. Herein, we report that a …
Mn3O4 Nanozyme for Inflammatory Bowel Disease Therapy
Y Cheng, C Cheng, J Yao, Y Yu, Y Liu… - Advanced …, 2021 - Wiley Online Library
Recently, reactive oxygen species (ROS) scavenging nanozymes have been developed as
natural enzyme alternatives to treat inflammatory bowel disease (IBD) as well as other …
natural enzyme alternatives to treat inflammatory bowel disease (IBD) as well as other …
Self‐assembly of multi‐nanozymes to mimic an intracellular antioxidant defense system
Y Huang, Z Liu, C Liu, E Ju, Y Zhang… - Angewandte …, 2016 - Wiley Online Library
In this work, for the first time, we constructed a novel multi‐nanozymes cooperative platform
to mimic intracellular antioxidant enzyme‐based defense system. V2O5 nanowire served as …
to mimic intracellular antioxidant enzyme‐based defense system. V2O5 nanowire served as …
A manganese oxide nanozyme prevents the oxidative damage of biomolecules without affecting the endogenous antioxidant system
Biocompatible nanoparticles with an intrinsic ability to mimic the cellular antioxidant
enzymes are potential candidates for the development of new therapeutics for various …
enzymes are potential candidates for the development of new therapeutics for various …
Manganese‐Based Antioxidase‐Inspired Biocatalysts with Axial Mn−N5 Sites and 2D d‐π‐Conjugated Networks for Rescuing Stem Cell Fate
Constructing highly effective biocatalysts with controllable coordination geometry for
eliminating reactive oxygen species (ROS) to address the current bottlenecks in stem‐cell …
eliminating reactive oxygen species (ROS) to address the current bottlenecks in stem‐cell …
Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy
Here, an integrated cascade nanozyme with a formulation of Pt@ PCN222-Mn is developed
to eliminate excessive reactive oxygen species (ROS). This nanozyme mimics superoxide …
to eliminate excessive reactive oxygen species (ROS). This nanozyme mimics superoxide …
Construction of pH‐Dependent Nanozymes with Oxygen Vacancies as the High‐Efficient Reactive Oxygen Species Scavenger for Oral‐Administrated Anti …
N Zhao, FE Yang, CY Zhao, SW Lv… - Advanced …, 2021 - Wiley Online Library
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
Ligand‐dependent activity engineering of glutathione peroxidase‐mimicking MIL‐47 (V) metal–organic framework nanozyme for therapy
J Wu, Y Yu, Y Cheng, C Cheng, Y Zhang… - Angewandte …, 2021 - Wiley Online Library
Glutathione peroxidase (GPx) plays an important role in maintaining the reactive oxygen
metabolic balance, yet limited GPx‐mimicking nanozymes are currently available for in vivo …
metabolic balance, yet limited GPx‐mimicking nanozymes are currently available for in vivo …