Mapping the human connectome using diffusion MRI at 300 mT/m gradient strength: Methodological advances and scientific impact

Q Fan, C Eichner, M Afzali, L Mueller, CMW Tax… - Neuroimage, 2022 - Elsevier
Tremendous efforts have been made in the last decade to advance cutting-edge MRI
technology in pursuit of mapping structural connectivity in the living human brain with …

[HTML][HTML] Using diffusion MRI data acquired with ultra-high gradient strength to improve tractography in routine-quality data

C Maffei, C Lee, M Planich, M Ramprasad, N Ravi… - Neuroimage, 2021 - Elsevier
The development of scanners with ultra-high gradient strength, spearheaded by the Human
Connectome Project, has led to dramatic improvements in the spatial, angular, and diffusion …

MGH–USC Human Connectome Project datasets with ultra-high b-value diffusion MRI

Q Fan, T Witzel, A Nummenmaa, KRA Van Dijk… - Neuroimage, 2016 - Elsevier
Abstract The MGH–USC CONNECTOM MRI scanner housed at the Massachusetts General
Hospital (MGH) is a major hardware innovation of the Human Connectome Project (HCP) …

[HTML][HTML] Connectome 2.0: Developing the next-generation ultra-high gradient strength human MRI scanner for bridging studies of the micro-, meso-and macro …

SY Huang, T Witzel, B Keil, A Scholz, M Davids, P Dietz… - NeuroImage, 2021 - Elsevier
The first phase of the Human Connectome Project pioneered advances in MRI technology
for mapping the macroscopic structural connections of the living human brain through the …

The Human Connectome Project and beyond: initial applications of 300 mT/m gradients

JA McNab, BL Edlow, T Witzel, SY Huang, H Bhat… - Neuroimage, 2013 - Elsevier
The engineering of a 3 T human MRI scanner equipped with 300 mT/m gradients–the
strongest gradients ever built for an in vivo human MRI scanner–was a major component of …

[HTML][HTML] Resolution and b value dependent structural connectome in ex vivo mouse brain

S Crater, S Maharjan, Y Qi, Q Zhao, G Cofer, JC Cook… - Neuroimage, 2022 - Elsevier
Diffusion magnetic resonance imaging has been widely used in both clinical and preclinical
studies to characterize tissue microstructure and structural connectivity. The diffusion MRI …

Pushing the limits of in vivo diffusion MRI for the Human Connectome Project

K Setsompop, R Kimmlingen, E Eberlein, T Witzel… - Neuroimage, 2013 - Elsevier
Perhaps more than any other “-omics” endeavor, the accuracy and level of detail obtained
from mapping the major connection pathways in the living human brain with diffusion MRI …

Comprehensive diffusion MRI dataset for in vivo human brain microstructure mapping using 300 mT/m gradients

Q Tian, Q Fan, T Witzel, MN Polackal, NA Ohringer… - Scientific data, 2022 - nature.com
Strong gradient systems can improve the signal-to-noise ratio of diffusion MRI
measurements and enable a wider range of acquisition parameters that are beneficial for …

Building connectomes using diffusion MRI: why, how and but

SN Sotiropoulos, A Zalesky - NMR in Biomedicine, 2019 - Wiley Online Library
Why has diffusion MRI become a principal modality for mapping connectomes in vivo? How
do different image acquisition parameters, fiber tracking algorithms and other …

[HTML][HTML] Quantitative mapping of the brain's structural connectivity using diffusion MRI tractography: A review

F Zhang, A Daducci, Y He, S Schiavi, C Seguin… - Neuroimage, 2022 - Elsevier
Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging
technique that enables in vivo reconstruction of the brain's white matter connections at …