Human pluripotent stem cells (hPSCs), which include human embryonic stem cells (hESCs)
and human induced pluripotent stem cells (hiPSCs), infinitely self-renew, and can …

Retrovirus is frequently used in the genetic modification of mammalian cells and the
establishment of induced pluripotent stem cells (iPSCs) via cell reprogramming. Vector …

The generation of human induced pluripotent stem cells (hiPSCs) opens a prospect for
regenerative medicine. However, transplantation of somatic cells derived from hiPSCs still …

Induced pluripotent stem cell (iPSC) technology has emerged as the most promising method
for generating patient-specific human embryonic stem (ES) cells and adult stem cells …

Human pluripotent stem cells (PSCs) express human endogenous retrovirus type-H (HERV-
H), which exists as more than a thousand copies on the human genome and frequently …

Stem cell therapies show great potential for use in regenerative medicine, though
advancements in safe stem cell technology need to be realized. Human induced pluripotent …

Despite many advances in human embryonic stem cell (hESC) technology the ethical
dilemma involving the destruction of a human embryo is one factor that has limited the …

Human pluripotent stem cells (hPSCs) are a promising source of regenerative material for
clinical applications. However, hPSC transplant therapies pose the risk of teratoma …

With sequence similarities to exogenous retroviruses, the proviral DNA elements named
endogenous retroviruses (ERVs) make up∼ 8% of human genome, threatening genomic …

Human endogenous retrovirus type-H (HERVH) is specifically expressed in the pluripotent
stem cells of the pre-implantation embryo. A subset of these elements appear to exert …