Screening and single-crystal growth of cocrystals is a time-consuming process, typically
performed by solution crystallization. Here we reported a case that a single pterostilbene …

New multicomponent solid forms of the nutraceutical pterostilbene have been discovered
and characterized through experimental cocrystal screening. Among the coformers tested …

The crystal structures of two new polymorphs of the 1/1 pterostilbene/picolinic acid cocrystal
have been analyzed by single-crystal X-ray diffraction and studied by means of DFT …

Pharmaceutical cocrystals are mixed crystals that contain two or more different molecular
components. These crystals usually present different characteristics from their precursor, an …

Cocrystal screening and single-crystal growth remain the primary obstacles in the
development of pharmaceutical cocrystals. Here, we present a new approach for cocrystal …

The crystalline nutritional supplement α-lipoic acid degrades rapidly on exposure to
temperatures above its melting point 65° C and to light. A small-scale experimental co …

Pharmaceutical cocrystals comprise one active pharmaceutical ingredient (API) and at least
one small molecule excipient coformer. While solvent evaporation and mechanochemistry …

In this feature article we will focus on the issues relating to the crystal growth of co-crystals,
with a particular emphasis on drug development. The initial focus of this perspective is on …

Cocrystals of 2, 4, 6, 8, 10, 12-hexanitrohexaazaisowurtzitane (CL-20) and 2, 4-dinitro-2, 4-
diazapentane (DNDAP) in a 2: 1 molar ratio were prepared by both slow evaporation and …

The competition between cocrystallization and separated crystallization in a solvent was
explored via X-ray diffraction and high-performance liquid chromatography methods in …