Noncommunicable diseases are chronic diseases that contribute to death worldwide, but
these diseases can be prevented and mitigated with regular exercise. Exercise activates …

AMPK (AMP-activated protein kinase) is a phylogenetically conserved fuel-sensing enzyme
that is present in all mammalian cells. During exercise, it is activated in skeletal muscle in …

Metabolic syndrome is characterized by a cluster of metabolic disorders, such as reduced
glucose tolerance, hyperinsulinemia, hypertension, visceral obesity and lipid disorders. The …

AMP-activated protein kinase (AMPK) has been postulated as a super-metabolic regulator,
thought to exert numerous effects on skeletal muscle function, metabolism, and enzymatic …

ABSTRACT HARDIE, DG AMP-Activated Protein Kinase: A Key System Mediating Metabolic
Responses to Exercise. Med. Sci. Sports Exerc., Vol. 36, No. 1, pp. 28–34, 2004. The finding …

ABSTRACT AMP‐activated protein kinase (AMPK) is a sensor of cellular energy status that
plays a central role in skeletal muscle metabolism. We used skeletal muscle‐specific …

Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …

Since the discovery of AMP-activated protein kinase (AMPK) as a central regulator of energy
homeostasis, many exciting insights into its structure, regulation and physiological roles …

The AMP-activated protein kinase (AMPK) is a heterotrimeric complex with central roles in
cellular energy sensing and the regulation of metabolism and exercise adaptations. AMPK …

The energy/fuel sensor 5′-AMP-activated protein kinase (AMPK) is viewed as a master
regulator of cellular energy balance due to its many roles in glucose, lipid, and protein …