Atherosclerosis is a chronic inflammatory disorder characterized by the gradual buildup of
plaques within the vessel wall of middle-sized and large arteries. The occurrence and …

Pyroptosis is a special way of programmed cell death which is dependent on the activation
of cysteinyl aspartate specific proteinase 1 (Caspase-1) and Caspase-4/5/11. Ferroptosis is …

Vascular endothelial cells (VECs), which are lined up in the inner surface of blood vessels,
are in direct contact with the metabolite-related endogenous danger signals in the …

Atherosclerosis (AS) is a major cause of cardiovascular diseases such as coronary heart
disease, heart failure and stroke. Abnormal lipid metabolism, oxidative stress and …

In advanced atherosclerosis (AS), defective function-induced cell death leads to the
formation of the characteristic necrotic core and vulnerable plaque. The forms and …

Ferroptosis is a newly identified form of non-apoptotic programmed cell death, characterized
by the iron-dependent accumulation of lethal lipid reactive oxygen species (ROS) and …

Cell death and inflammation are the fundamental biological processes in both normal
physiology and pathology. Apoptosis is the most well-studied process of cell death, but there …

Cardiovascular disease (CVD), including heart attack, stroke, heart failure, arrhythmia, and
other congenital heart diseases remain the leading cause of morbidity and mortality …

The concept of cell death has been expanded beyond apoptosis and necrosis to additional
forms, including necroptosis, pyroptosis, autophagy, and ferroptosis. These cell death …

Simple Summary Ferroptosis is a type of cell death, which is morphologically and
mechanistically distinct from other type of cell death pathways such as apoptosis and …