Involvement of the innate immune system in the pathogenesis of chronic obstructive pulmonary disease

S Kotlyarov - International Journal of Molecular Sciences, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a common, socially significant disease
characterized by progressive airflow limitation due to chronic inflammation in the bronchi …

An insight into COPD morphopathogenesis: Chronic inflammation, remodeling, and antimicrobial defense

Z Vitenberga, M Pilmane, A Babjoniševa - Medicina, 2019 - mdpi.com
Background and Objectives: Intercellular signaling networks with high complexity cause a
spectrum of mechanisms achieving chronic obstructive pulmonary disease (COPD) that still …

Lung macrophage functional properties in chronic obstructive pulmonary disease

K Akata, SF van Eeden - International journal of molecular sciences, 2020 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is caused by the chronic exposure of the
lungs to toxic particles and gases. These exposures initiate a persistent innate and adaptive …

Lung macrophage phenotypes and functional responses: role in the pathogenesis of COPD

K Yamasaki, SF van Eeden - International journal of molecular sciences, 2018 - mdpi.com
Lung macrophages (LMs) are essential immune effector cells that are pivotal in both innate
and adaptive immune responses to inhaled foreign matter. They either reside within the …

Cellular and molecular mechanisms of chronic obstructive pulmonary disease

PJ Barnes - Clinics in chest medicine, 2014 - chestmed.theclinics.com
Chronic obstructive pulmonary disease (COPD) involves chronic inflammation of the lung,
particularly in peripheral airways and parenchyma, which increases during acute …

Pathogenesis of chronic obstructive pulmonary disease

W MacNee - Clinics in chest medicine, 2007 - Elsevier
The pathogenesis of chronic obstructive pulmonary disease (COPD) encompasses a
number of injurious processes, including an abnormal inflammatory response in the lungs to …

[PDF][PDF] Imunopatogenesis penyakit paru obstruktif kronik

R Yudhawati, YD Prasetiyo - J Respirasi, 2019 - e-journal.unair.ac.id
ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory airway
disease and complicated lung tissue. The airways of patients with COPD contain many …

Aspects on pathophysiological mechanisms in COPD

K Larsson - Journal of internal medicine, 2007 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a condition which is characterized by
irreversible airway obstruction due to narrowing of small airways, bronchiolitis, and …

Molecular characteristics and treatment of endothelial dysfunction in patients with COPD: a review article

B Szucs, C Szucs, M Petrekanits, JT Varga - International journal of …, 2019 - mdpi.com
Patients with chronic obstructive pulmonary disease (COPD) show systemic consequences,
such as chronic systemic inflammation leading to changes in the airway, airway …

Biomarkers for comorbidities modulate the activity of T-cells in COPD

K Jamal Jameel, WJ Gallert, SD Yanik, S Panek… - International journal of …, 2021 - mdpi.com
In smoking-induced chronic obstructive pulmonary disease (COPD), various comorbidities
are linked to systemic inflammation and infection-induced exacerbations. The underlying …