Lateral habenula and its potential roles in pain and related behaviors
D Dai, W Li, A Chen, XF Gao… - ACS chemical …, 2022 - ACS Publications
The lateral habenula (LHb) is a tiny structure that acts as a hub, relaying signals from the
limbic forebrain structures and basal ganglia to the brainstem modulatory area. Facilitated …
limbic forebrain structures and basal ganglia to the brainstem modulatory area. Facilitated …
Lateral habenula serves as a potential therapeutic target for neuropathic pain
Y Du, YX Wu, F Guo, FH Qu, TT Hu, B Tan, Y Wang… - Neuroscience …, 2021 - Springer
Neuropathic pain (NeuP) is known as a common and notorious neurological disease,
characterized by spontaneous pain and evoked abnormal pain that includes hypersensitivity …
characterized by spontaneous pain and evoked abnormal pain that includes hypersensitivity …
Circuits and functions of the lateral habenula in health and in disease
H Hu, Y Cui, Y Yang - Nature Reviews Neuroscience, 2020 - nature.com
The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …
owing to new discoveries relating to its critical role in regulating negatively motivated …
[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation
Over the last decade, the understanding of the habenula has rapidly advanced from being
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
[HTML][HTML] Lateral habenula in the pathophysiology of depression
Depression is a devastating disorder with a combination of diverse symptoms such as low
self-esteem, lack of motivation, anhedonia, loss of appetite, low energy, and discomfort …
self-esteem, lack of motivation, anhedonia, loss of appetite, low energy, and discomfort …
[HTML][HTML] Dysregulation of the lateral habenula in major depressive disorder
CA Browne, R Hammack, I Lucki - Frontiers in synaptic neuroscience, 2018 - frontiersin.org
Clinical and preclinical evidence implicates hyperexcitability of the lateral habenula (LHb) in
the development of psychiatric disorders including major depressive disorder (MDD). This …
the development of psychiatric disorders including major depressive disorder (MDD). This …
[HTML][HTML] Synaptic and cellular profile of neurons in the lateral habenula
The lateral habenula (LHb) is emerging as a crucial structure capable of conveying
rewarding and aversive information. Recent evidence indicates that a rapid increase in the …
rewarding and aversive information. Recent evidence indicates that a rapid increase in the …
The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview
The lateral habenula (LH b) is an epithalamic region with a crucial role in the regulation of
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …
Unmasking the mysteries of the habenula in pain and analgesia
L Shelton, L Becerra, D Borsook - Progress in neurobiology, 2012 - Elsevier
The habenula is a small bilateral structure in the posterior–medial aspect of the dorsal
thalamus that has been implicated in a remarkably wide range of behaviors including …
thalamus that has been implicated in a remarkably wide range of behaviors including …
[HTML][HTML] The role of the habenula in drug addiction
KM Velasquez, DL Molfese, R Salas - Frontiers in human …, 2014 - frontiersin.org
Interest in the habenula has greatly increased in recent years. The habenula is a small brain
structure located posterior to the thalamus and adjacent to the third ventricle. Despite its …
structure located posterior to the thalamus and adjacent to the third ventricle. Despite its …