Manifestations of cardiovascular diseases (CVDs) in a patient or a population differ based
on inherent biological makeup, lifestyle, and exposure to environmental risk factors. These …

Disease models are essential for understanding cardiovascular disease pathogenesis and
developing new therapeutics. The human induced pluripotent stem cell (iPSC) technology …

Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for
regenerative therapy, disease modeling, and drug discovery. iPSCs allow for the production …

The discovery of induced pluripotent stem cells (iPSC) has, in the short time since their
discovery, revolutionized the field of stem cell biology. This technology allows the generation …

The generation of cardiomyocytes from human induced pluripotent stem cells (hiPSCs)
provides a source of cells that accurately recapitulate the human cardiac pathophysiology …

Induced pluripotent stem cells (iPSCs) offer an unprece-dented opportunity to study human
physiology and disease at the cellular level. They also have the potential to be leveraged in …

Technical advances in generating and phenotyping cardiomyocytes from human pluripotent
stem cells (hPSC-CMs) are now driving their wider acceptance as in vitro models to …

Advances in our understanding of cardiovascular development have provided a roadmap for
the directed differentiation of human pluripotent stem cells (hPSCs) to the major cell types …

The prospect of changing the plasticity of terminally differentiated cells toward pluripotency
has completely altered the outlook for biomedical research. Human-induced pluripotent …

Induced pluripotent stem cells (iPSCs) offer great promise in the areas of disease modeling,
basic research, drug development, and regenerative medicine. Much of their value comes …