Antipersister strategies against stress induced bacterial persistence
The increase in antibiotic non-responsive bacteria is the leading concern in current research
oriented to eliminate pathogens. Nowadays, the excess use of antibiotics without specifically …
oriented to eliminate pathogens. Nowadays, the excess use of antibiotics without specifically …
Link between antibiotic persistence and antibiotic resistance in bacterial pathogens
W Eisenreich, T Rudel, J Heesemann… - Frontiers in cellular and …, 2022 - frontiersin.org
Both, antibiotic persistence and antibiotic resistance characterize phenotypes of survival in
which a bacterial cell becomes insensitive to one (or even) more antibiotic (s). However, the …
which a bacterial cell becomes insensitive to one (or even) more antibiotic (s). However, the …
[HTML][HTML] Slow and steady wins the race: an examination of bacterial persistence
TL Renbarger, JM Baker, WM Sattley - AIMS microbiology, 2017 - ncbi.nlm.nih.gov
Bacterial persistence is a state of metabolic dormancy among a small fraction (< 1%) of a
genetically identical population of cells that, as a result, becomes transiently resistant to …
genetically identical population of cells that, as a result, becomes transiently resistant to …
[PDF][PDF] What are the options for treating infections by persister-forming pathogens?
L Fernández-García, JM Muthami, M Tomas… - Environ …, 2022 - sites.psu.edu
Persistence is the non-heritable state of dormancy of a small subset of cells that allows these
cells to survive a wide range of stresses. These stresses include antibiotics at concentrations …
cells to survive a wide range of stresses. These stresses include antibiotics at concentrations …
Bacterial persisters and infection: past, present, and progressing
B Gollan, G Grabe, C Michaux… - Annual review of …, 2019 - annualreviews.org
Persisters are nongrowing, transiently antibiotic-tolerant bacteria within a clonal population
of otherwise susceptible cells. Their formation is triggered by environmental cues and …
of otherwise susceptible cells. Their formation is triggered by environmental cues and …
Persistence of intracellular bacterial pathogens—With a focus on the metabolic perspective
W Eisenreich, T Rudel, J Heesemann… - Frontiers in Cellular and …, 2021 - frontiersin.org
Persistence has evolved as a potent survival strategy to overcome adverse environmental
conditions. This capability is common to almost all bacteria, including all human bacterial …
conditions. This capability is common to almost all bacteria, including all human bacterial …
Molecular mechanisms underlying bacterial persisters
E Maisonneuve, K Gerdes - Cell, 2014 - cell.com
All bacteria form persisters, cells that are multidrug tolerant and therefore able to survive
antibiotic treatment. Due to the low frequencies of persisters in growing bacterial cultures …
antibiotic treatment. Due to the low frequencies of persisters in growing bacterial cultures …
Ecology and evolution of antibiotic persistence
L Verstraete, B Van den Bergh, N Verstraeten… - Trends in …, 2022 - cell.com
Bacteria have at their disposal a battery of strategies to withstand antibiotic stress. Among
these, resistance is a well-known mechanism, yet bacteria can also survive antibiotic attack …
these, resistance is a well-known mechanism, yet bacteria can also survive antibiotic attack …
A problem of persistence: still more questions than answers?
NQ Balaban, K Gerdes, K Lewis… - Nature Reviews …, 2013 - nature.com
The current antibiotic resistance crisis has led to increased pressure to prioritize strategies to
tackle the issue, with a strong focus being placed on the development of novel …
tackle the issue, with a strong focus being placed on the development of novel …
Antibiotic persistence as a metabolic adaptation: stress, metabolism, the host, and new directions
Persistence is a phenomenon during which a small fraction of a total bacterial population
survives treatment with high concentrations of antibiotics for an extended period of time. In …
survives treatment with high concentrations of antibiotics for an extended period of time. In …