Telomerase reverse transcriptase (TERT) is expressed by quiescent adult stem cells (qASC)
in numerous adult murine and human tissues but has never been explored in the adult …

Telomerase reverse transcriptase (TERT) is expressed by quiescent adult stem cells (ASC)
in numerous adult murine and human tissues, but has never been explored in the adult …

Age is the greatest risk factor for Alzheimer's disease and aging is associated with the
shortening of telomeres, the terminal regions of chromosomes. A new study shows that …

A telomerase reverse transcriptase (Tert) lineage-tracing mouse line was developed to
investigate the behavior and fate of adult tissue stem cells, by crossing the'Tet-On'system …

The molecular, biochemical and cellular events that result in synaptic dysfunction and
neuronal degeneration in the brain in Alzheimer's disease (AD) are becoming known. Age …

Changes in telomerase activity and telomere length contribute to aging-related decline.
Investigating telomerase in aging models provides insights into related pathologies. Here …

For almost three decades, neural stem cells remain still up-to-date and enigmatic topic. The
main problem for their studying is the non-existence of an exclusive neural stem cell marker …

Telomere dysfunction-induced loss of genome integrity and its associated DNA damage
signaling and checkpoint responses are well-established drivers that cause tissue …

Restoring adult stem cell function provides an exciting approach for rejuvenating the aging
brain. However, molecular mechanisms mediating neurogenic rejuvenation remain elusive …

Amyloid-induced neurodegeneration plays a central role in Alzheimer's disease (AD)
pathogenesis. Here, we show that telomerase reverse transcriptase (TERT) …