Targeting Cancer Metabolism with Isoselenazolium Salts. Doctoral Thesis

P Dimitrijevs - 2024 - dspace.rsu.lv
Low therapeutic efficacy and resistance to conventional drugs remain the major obstacles in
modern chemotherapy. Scientists around the world are therefore constantly searching for …

[图书][B] Organoselenium compounds in biology and medicine: synthesis, biological and therapeutic treatments

VK Jain, KI Priyadarsini - 2017 - books.google.com
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This
book discusses organoselenium chemistry and biology in the context of its therapeutic …

[HTML][HTML] Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment

V Gandin, P Khalkar, J Braude… - Free Radical Biology and …, 2018 - Elsevier
Selenium (Se)-containing compounds have attracted a growing interest as anticancer
agents over recent decades, with mounting reports demonstrating their high efficacy and …

Organoselenium Compounds in Medicinal Chemistry

C Gallo‐Rodriguez, JB Rodriguez - ChemMedChem, 2024 - Wiley Online Library
The chemical and biological interest in this element and the molecules bearing selenium
has been exponentially growing over the years. Selenium, formerly designated as a toxin …

Diselenides and selenocyanates as versatile precursors for the synthesis of pharmaceutically relevant compounds

MD Kostić, VM Divac - Current Organic Synthesis, 2022 - ingentaconnect.com
Organoselenium chemistry has undergone extensive development during the past decades,
mostly due to the unique chemical properties of organoselenium compounds that have been …

Incorporating selenium into heterocycles and natural products─ from chemical properties to pharmacological activities

W Hou, H Xu - Journal of Medicinal Chemistry, 2022 - ACS Publications
Selenium (Se)-containing compounds have emerged as potential therapeutic agents for the
treatment of a range of diseases. Through tremendous effort, considerable knowledge has …

Therapeutic potential of selenium compounds in the treatment of cancer

AK Selvam, M Björnstedt, S Misra - Selenium, 2018 - Springer
The potential applications of different selenium compounds as cancer chemotherapeutic
agents is an active area of research within the field of cancer drug discovery. The …

[HTML][HTML] Novel methylselenoesters as antiproliferative agents

N Díaz-Argelich, I Encío, D Plano, AP Fernandes… - Molecules, 2017 - mdpi.com
Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the
biological effects of Se compounds are exerted by their metabolites, with methylselenol …

Selenium compounds as therapeutic agents in cancer

AP Fernandes, V Gandin - Biochimica et Biophysica Acta (BBA)-General …, 2015 - Elsevier
Background With cancer cells encompassing consistently higher production of reactive
oxygen species (ROS) and with an induced antioxidant defense to counteract the increased …

Selenium-containing heterocycles

H Xu, W Hou - Privileged Scaffolds in Drug Discovery, 2023 - Elsevier
As an essential trace element, selenium (Se) has become an emerging versatile player in
heterocycles and natural product modifications. Numerous organoselenium (org-Se) …