Development and Analytical Characterization of Lipid-Based Nanoparticles

M Yu - 2022 - deepblue.lib.umich.edu
Lipid-based nanoparticles are highly versatile platforms with extensive therapeutic
applications. Despite rapid scientific advances in the past several decades, clinical …

Evaluation of Lipid-Based Nanoparticles for the Treatment of Cardiovascular Diseases

K Hong Dorsey - 2024 - deepblue.lib.umich.edu
Nearly 17.9 million people die every year from cardiovascular-related diseases, which
accounts for 31% of all deaths worldwide. Endogenous high-density lipoproteins (HDL) are …

Optimization of synthetic high-density lipoprotein nanostructures for treatment of inflammatory diseases

SY Kim - 2019 - deepblue.lib.umich.edu
Biomimetic synthetic high-density lipoproteins (sHDLs) are nanoparticles that mimic the
physical, chemical, and biological activity of endogenous HDL. A number of sHDL products …

[PDF][PDF] The Science of Solid Lipid Nanoparticles: From Fundamentals to Applications

S Sangeetha, D Narayanasamy - Cureus, 2024 - cureus.com
Solid lipid nanoparticles (SLNs) play a crucial role in drug delivery, offering benefits such as
enhanced bioavailability, targeted distribution, and reduced toxicity. This article provides a …

Encapsulation challenges, the substantial issue in solid lipid nanoparticles characterization

S Daneshmand, S Golmohammadzadeh… - Journal of cellular …, 2018 - Wiley Online Library
Solid lipid nanoparticles (SLNs), as alternative colloidal carriers, have been used for the
sustained release of lipophilic drugs with poor water solubility. One of the most important …

Solid lipid nanoparticles: a current approach to new drug-delivery systems in nanotechnology

S Dhiman, TG Singh, A Asthana, S Arora, M Jindal - 2013 - Taylor & Francis
Solid lipid nanoparticles (SLNs) were introduced two decades ago and represent a
replacement to the shortcomings of conventional colloidal carrier systems, such as …

[PDF][PDF] Lipid Nano-Carrier Systems for Inflammatory Diseases

S Khawas, K Anand, N Sharma - Lipid Based Nanocarriers for …, 2024 - researchgate.net
This chapter presents a platform that outlines diverse lipid nanocarrier approaches intended
for various inflammatory diseases. It capitalizes on the rapidly evolving domain of lipid …

Templated high density lipoprotein nanoparticles as potential therapies and for molecular delivery

MG Damiano, RK Mutharasan, S Tripathy… - Advanced drug delivery …, 2013 - Elsevier
High density lipoproteins (HDLs) are dynamic natural nanoparticles best known for their role
in cholesterol transport and the inverse correlation that exists between blood HDL levels and …

Chemistry and art of developing lipid nanoparticles for biologics delivery: focus on development and scale-up

R John, J Monpara, S Swaminathan, R Kalhapure - Pharmaceutics, 2024 - mdpi.com
Lipid nanoparticles (LNPs) have gained prominence as primary carriers for delivering a
diverse array of therapeutic agents. Biological products have achieved a solid presence in …

Probing nanoliposomes using single particle analytical techniques: Effect of excipients, solvents, phase transition and zeta potential

M Danaei, M Kalantari, M Raji, HS Fekri, R Saber… - Heliyon, 2018 - cell.com
There has been a steady increase in the interest towards employing nanoliposomes as
colloidal drug delivery systems, particularly in the last few years. Their biocompatibility …