Nanoparticle-based drug delivery systems in cancer: A focus on inflammatory pathways

AR Afshari, M Sanati, H Mollazadeh… - Seminars in cancer …, 2022 - Elsevier
It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment

M Kanapathipillai, A Brock, DE Ingber - Advanced drug delivery reviews, 2014 - Elsevier
Nanoparticle-based therapeutics are poised to become a leading delivery strategy for
cancer treatment because they potentially offer higher selectivity, reduced toxicity, longer …

The application of nanotechnology in enhancing immunotherapy for cancer treatment: current effects and perspective

Y Li, C Ayala-Orozco, PR Rauta, S Krishnan - Nanoscale, 2019 - pubs.rsc.org
Cancer immunotherapy is emerging as a promising treatment modality that suppresses and
eliminates tumors by re-activating and maintaining the tumor-immune cycle, and further …

[HTML][HTML] Nanomedicine-based drug delivery towards tumor biological and immunological microenvironment

J Li, DJ Burgess - Acta Pharmaceutica Sinica B, 2020 - Elsevier
The complex tumor microenvironment is a most important factor in cancer development. The
biological microenvironment is composed of a variety of barriers including the extracellular …

Nanoparticle-mediated remodeling of the tumor microenvironment to enhance immunotherapy

S Musetti, L Huang - ACS nano, 2018 - ACS Publications
Nanoscience has long been lauded as a method through which tumor-associated barriers
could be overcome. As successful as cancer immunotherapy has been, limitations …

New strategies in cancer nanomedicine

R Tong, DS Kohane - Annual review of pharmacology and …, 2016 - annualreviews.org
We review recent progress in cancer nanomedicine, including stimulus-responsive drug
delivery systems and nanoparticles responding to light for phototherapy or tumor imaging. In …

Current nano-therapeutic approaches ameliorating inflammation in cancer progression

MU Rehman, A Khan, Z Imtiyaz, S Ali… - Seminars in cancer …, 2022 - Elsevier
Cancer is one of the biggest causes of mortality in the world. The advances in cancer
research have taken us to distance in understanding the disease, which helps develop …

Nanoparticle‐based nanomedicines to promote cancer immunotherapy: recent advances and future directions

J Liu, R Zhang, ZP Xu - Small, 2019 - Wiley Online Library
Cancer immunotherapy is a promising cancer terminator by directing the patient's own
immune system in the fight against this challenging disorder. Despite the monumental …

Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

[HTML][HTML] Re-establishing the comprehension of phytomedicine and nanomedicine in inflammation-mediated cancer signaling

NK Jha, S Arfin, SK Jha, R Kar, A Dey… - Seminars in Cancer …, 2022 - Elsevier
Recent mounting evidence has revealed extensive genetic heterogeneity within tumors that
drive phenotypic variation affecting key cancer pathways, making cancer treatment …