Integrated multi-omics reveals the beneficial roles of chlorogenic acid in improving the immune function of immunologically-stressed broilers

H Liu, X Li, K Zhang, X Lv, Q Zhang, P Chen, Y Wang… - 2022 - researchsquare.com
Background: Commercial broilers under intensive production are highly vulnerable to
various stressors, especially immunologically. It has been reported that chlorogenic acid …

[HTML][HTML] Integrated multi-omics reveals the beneficial role of chlorogenic acid in improving the growth performance and immune function of immunologically stressed …

H Liu, X Li, K Zhang, X Lv, Q Zhang, P Chen, Y Wang… - Animal Nutrition, 2023 - Elsevier
Intensive production can cause immunological stress in commercial broilers. Chlorogenic
acid (CGA) regulates the intestinal microbiota, barrier function, and immune function in …

[HTML][HTML] Effects of dietary chlorogenic acid on cecal microbiota and metabolites in broilers during lipopolysaccharide-induced immune stress

X Hu, W Zhen, D Bai, J Zhong, R Zhang… - Frontiers in …, 2024 - frontiersin.org
Aims The aim of this study was to investigate the effects of chlorogenic acid (CGA) on the
intestinal microorganisms and metabolites in broilers during lipopolysaccharide (LPS) …

[HTML][HTML] Dietary supplementation with chlorogenic acid enhances antioxidant capacity, which promotes growth, jejunum barrier function, and cecum microbiota in …

Y Liu, Y Zhang, D Bai, Y Li, X He, K Ito, K Liu, H Tan… - Animals, 2023 - mdpi.com
Simple Summary High density (HD) rearing seriously hinders the healthy development of
broilers. Chlorogenic acid, a natural antioxidant food and drug source, may relieve the HD …

[HTML][HTML] Effects of dietary chlorogenic acid on ileal intestinal morphology, barrier function, immune factors and gut microbiota of broilers under high stocking density …

YQ Li, Y Zhang, DY Bai, YH Liu, XL He, K Ito… - Frontiers in …, 2023 - frontiersin.org
Aims: The purpose of this research was to assess the effect of chlorogenic acid (CGA) in the
diet on ileac structure, barrier function, immunological state, and microbial profile of broiler …

Protective effects of chlorogenic acid on the meat quality of oxidatively stressed broilers revealed by integrated metabolomics and antioxidant analysis

K Zhang, X Li, J Zhao, Y Wang, X Hao, K Liu, H Liu - Food & Function, 2022 - pubs.rsc.org
Oxidation is a major cause of meat quality deterioration during broiler production, which
leads to undesirable meat color and impaired water holding capacity (WHC), thereby …

[HTML][HTML] Integrating serum metabolome and gut microbiome to evaluate the benefits of lauric acid on lipopolysaccharide-challenged broilers

Y Wu, Q Li, J Liu, Y Liu, Y Xu, R Zhang, Y Yu… - Frontiers in …, 2021 - frontiersin.org
Lauric acid (LA) is a crucial medium-chain fatty acid (MCFA) that has many beneficial effects
on humans and animals. This study aimed to investigate the effects of LA on the intestinal …

Quantitative Phosphoproteomics Analysis Reveals the Protective Mechanism of Chlorogenic Acid on Immunologically Stressed Broiler Meat Quality

K Zhang, H Meng, M Du, Y Du, X Li… - Journal of Agricultural …, 2024 - ACS Publications
Modern poultry production is stressful for the birds, and this stress is recognized as a major
cause of inferior meat quality. Chlorogenic acid (CGA), a plant phenolic acid, has excellent …

[HTML][HTML] Chlorogenic acid protects against intestinal inflammation and injury by inactivating the mtDNA–cGAS–STING signaling pathway in broilers under necrotic …

H Lv, P Chen, Y Wang, L Xu, K Zhang, J Zhao, H Liu - Poultry Science, 2024 - Elsevier
This study aimed to determine the effects of chlorogenic acid (CGA) on the growth
performance, intestinal health, immune response, and mitochondrial DNA (mtDNA)–cyclic …

[HTML][HTML] Chlorogenic acid improves growth performance and intestinal health through autophagy-mediated nuclear factor erythroid 2-related factor 2 pathway in …

H Liu, X Li, S Shi, Y Zhou, K Zhang, Y Wang, J Zhao - Poultry Science, 2022 - Elsevier
The effects of chlorogenic acid (CGA) on growth performance, intestinal morphology,
antioxidant capacity, and the autophagy-mediated nuclear factor erythroid 2-related factor 2 …