Abstract ADNP encodes Activity-Dependent Neuroprotective Protein, whose de novo
heterozygous mutations cause Helsmoortel-Van der Aa Syndrome (HVDAS), a rare …

Background Individuals affected with autism often suffer additional co-morbidities such as
intellectual disability. The genes contributing to autism cluster on a relatively limited number …

Autism spectrum disorder (ASD) is a highly heritable and highly heterogeneous
neuropsychiatric condition whose cause is still unknown because there are no recurrent …

Gene ontology analyses of high-confidence autism spectrum disorder (ASD) risk genes
highlight chromatin regulation and synaptic function as major contributors to pathobiology …

Recent studies have identified over one hundred high-confidence (hc) autism spectrum
disorder (ASD) genes. Systems biological and functional analyses on smaller subsets of …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
significant and complex genetic etiology. GWAS studies have identified genetic variants …

Potentially pathogenic alterations have been identified in individuals with autism spectrum
disorders (ASDs) within a variety of key neurodevelopment genes. While this hints at a …

Three-dimensional chromatin structures regulate gene expression across genome. The
significance of de novo mutations (DNMs) affecting chromatin interactions in autism …

IntroductionThree-dimensional chromatin interactions regulate gene expressions. The
significance of de novo mutations (DNMs) in chromatin interactions remains poorly …

Autism spectrum disorder (ASD) is a range of major neurodevelopmental disabilities with a
strong genetic basis. Yet, owing to extensive genetic heterogeneity, multiple modes of …