Regulation of embryonic stem cell self-renewal
G Chen, S Yin, H Zeng, H Li, X Wan - Life, 2022 - mdpi.com
Embryonic stem cells (ESCs) are a type of cells capable of self-renewal and multi-directional
differentiation. The self-renewal of ESCs is regulated by factors including signaling pathway …
differentiation. The self-renewal of ESCs is regulated by factors including signaling pathway …
Transcriptional profiling of the developmentally important signalling pathways in human embryonic stem cells
BACKGROUND: Embryonic stem cells (ESC) maintain their 'stemness' by self-renewal.
However, the molecular mechanisms underlying self-renewal of human embryonic stem …
However, the molecular mechanisms underlying self-renewal of human embryonic stem …
Molecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency network
Embryonic stem cells (ESCs) can be maintained in culture indefinitely while retaining the
capacity to generate any type of cell in the body, and therefore not only hold great promise …
capacity to generate any type of cell in the body, and therefore not only hold great promise …
[HTML][HTML] Canonical wnt pathway controls mESC Self-renewal through inhibition of spontaneous differentiation via β-Catenin/TCF/LEF functions
The Wnt/β-catenin signaling pathway is a key regulator of embryonic stem cell (ESC) self-
renewal and differentiation. Constitutive activation of this pathway has been shown to …
renewal and differentiation. Constitutive activation of this pathway has been shown to …
Embryonic stem cell self‐renewal pathways converge on the transcription factor Tfcp2l1
S Ye, P Li, C Tong, QL Ying - The EMBO journal, 2013 - embopress.org
Mouse embryonic stem cell (mESC) self‐renewal can be maintained by activation of the
leukaemia inhibitory factor (LIF)/signal transducer and activator of transcription 3 (Stat3) …
leukaemia inhibitory factor (LIF)/signal transducer and activator of transcription 3 (Stat3) …
Dissecting signaling pathways that govern self-renewal of rabbit embryonic stem cells
S Wang, Y Shen, X Yuan, K Chen, X Guo… - Journal of Biological …, 2008 - ASBMB
The pluripotency and self-renewal of embryonic stem cells (ESC) are regulated by a variety
of cytokines/growth factors with some species differences. We reported previously that rabbit …
of cytokines/growth factors with some species differences. We reported previously that rabbit …
Tfcp2l1 safeguards the maintenance of human embryonic stem cell self‐renewal
H Sun, Y You, M Guo, X Wang… - Journal of Cellular …, 2018 - Wiley Online Library
Tfcp2l1 is a transcription factor critical for mouse embryonic stem cell (mESC) maintenance.
However, its role in human ESCs (hESCs) remains unclear. Here, we investigated the role of …
However, its role in human ESCs (hESCs) remains unclear. Here, we investigated the role of …
Molecular mechanisms involved in self‐renewal and pluripotency of embryonic stem cells
N Liu, M Lu, X Tian, Z Han - Journal of cellular physiology, 2007 - Wiley Online Library
Embryonic stem cells (ES cells) are derived from inner cell mass (ICM). The self‐renewal
and pluripotency are the main specificities of ES cells, which are likely to reveal a deeper …
and pluripotency are the main specificities of ES cells, which are likely to reveal a deeper …
Molecular mechanisms underlying pluripotency and self-renewal of embryonic stem cells
Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of the blastocyst.
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …
Single-stranded DNA binding protein Ssbp3 induces differentiation of mouse embryonic stem cells into trophoblast-like cells
J Liu, X Luo, Y Xu, J Gu, F Tang, Y Jin, H Li - Stem Cell Research & …, 2016 - Springer
Background Intrinsic factors and extrinsic signals which control unlimited self-renewal and
developmental pluripotency in embryonic stem cells (ESCs) have been extensively …
developmental pluripotency in embryonic stem cells (ESCs) have been extensively …
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