Embryonic stem cells (ESCs) are a type of cells capable of self-renewal and multi-directional
differentiation. The self-renewal of ESCs is regulated by factors including signaling pathway …

BACKGROUND: Embryonic stem cells (ESC) maintain their 'stemness' by self-renewal.
However, the molecular mechanisms underlying self-renewal of human embryonic stem …

Embryonic stem cells (ESCs) can be maintained in culture indefinitely while retaining the
capacity to generate any type of cell in the body, and therefore not only hold great promise …

The Wnt/β-catenin signaling pathway is a key regulator of embryonic stem cell (ESC) self-
renewal and differentiation. Constitutive activation of this pathway has been shown to …

Mouse embryonic stem cell (mESC) self‐renewal can be maintained by activation of the
leukaemia inhibitory factor (LIF)/signal transducer and activator of transcription 3 (Stat3) …

The pluripotency and self-renewal of embryonic stem cells (ESC) are regulated by a variety
of cytokines/growth factors with some species differences. We reported previously that rabbit …

Tfcp2l1 is a transcription factor critical for mouse embryonic stem cell (mESC) maintenance.
However, its role in human ESCs (hESCs) remains unclear. Here, we investigated the role of …

Embryonic stem cells (ES cells) are derived from inner cell mass (ICM). The self‐renewal
and pluripotency are the main specificities of ES cells, which are likely to reveal a deeper …

Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of the blastocyst.
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …

Background Intrinsic factors and extrinsic signals which control unlimited self-renewal and
developmental pluripotency in embryonic stem cells (ESCs) have been extensively …