Hypothermia is defined as a core body temperature of< 35° C, and as body temperature is
reduced the impact on physiological processes can be beneficial or detrimental. The …

In contrast to these positive findings, studies in patients with traumatic brain injury have
produced conflicting results [9, 10], and studies looking at short-term induction of …

Objective: To review human thermoregulation and the pathophysiology and management of
induced and accidental hypothermia. Data sources: A review of studies reported over ten …

The earliest recorded application of therapeutic hypothermia in medicine spans about 5000
years; however, its use has become widespread since 2002, following the demonstration of …

This review briefly discusses the history of induced therapeutic hypothermia (TH), which
represents the intentional induction of a lowered core body temperature of 35° C or less. The …

Background: Mild to moderate hypothermia (32–35 C) is the first treatment with proven
efficacy for postischemic neurological injury. In recent years important insights have been …

Samuel A. Tisherman, MD', Fritz Sterz, MD~'~ niversit~ of Pittsburgh, Pittsburgh, PA, USA 2~
edical University of Vienna, Vienna, Austria The use of hypothermia for a variety of …

Experimental evidence and clinical experience suggest that mild hypothermia protects
numerous tissues from damage during ischemic insult. However, the extent to which …

Objective Hypothermia has been used for medicinal purposes since ancient times. This
paper reviews the current potential clinical applications for mild hypothermia (32–35° C) …

Therapeutic hypothermia, an intervention reducing core body temperature below 35
degrees Celsius, has gained popularity in the management of acute brain injury after a …