Pathogenic enteric viruses are a major cause of morbidity and mortality, particularly among
children in developing countries. The host response to enteric viruses occurs primarily within …

Enteric viruses display intricate adaptations to the host mucosal immune system to
successfully reproduce in the gastrointestinal tract and cause maladies ranging from …

The intestinal microbiota exerts a marked influence in the mammalian host, both during
homeostasis and disease. However, until very recently, there has been relatively little focus …

Highlights•A normal microbiome shapes the immune system and promotes host
health.•Vaccine efficacy is altered by host, environmental, and viral factors.•The gut …

The intestine is an essential physical and immunological barrier comprised of a monolayer
of diverse and specialized epithelial cells that perform functions ranging from nutrient …

BACKGROUND Viruses that infect the mammalian gastrointestinal tract have intimate
relationships with the host, as well as members of the complex community of microbes that …

Enteric viruses encounter a multitude of environments as they traverse the gastrointestinal
tract. The interaction of enteric eukaryotic viruses with members of the host microbiota …

Background Acute diarrhoeal disease caused by viral, bacterial and parasitic infections is a
major global health problem; in low-and middle-income countries (LMICs) it is associated …

Enteric infections kill approximately two million children under the age of 5 in developing
countries and cause more than four billion disease episodes worldwide each year. In …

Enteroviruses are among the most common viral infectious agents of humans and are
primarily transmitted by the fecal–oral route. However, the events associated with …