Improving allogeneic stem cell transplantation in myelofibrosis

N Gagelmann, N Kröger - International Journal of Hematology, 2022 - Springer
In this review, we will outline dimensions in which outcome of patients with myelofibrosis
undergoing curative treatment can be optimized: patient selection, transplant procedure, and …

Impact of ruxolitinib pretreatment on outcomes after allogeneic stem cell transplantation in patients with myelofibrosis

S Shahnaz Syed Abd Kadir… - European Journal of …, 2018 - Wiley Online Library
Introduction Ruxolitinib is the first approved drug for treatment of myelofibrosis, but its impact
of outcome after allogeneic stem cell transplantation (ASCT) is unknown. Patients and …

[HTML][HTML] The role of allogeneic stem-cell transplant in myelofibrosis in the era of JAK inhibitors: a case-based review

M Tiribelli, F Palandri, E Sant'Antonio… - Bone Marrow …, 2020 - nature.com
Allogeneic hematopoietic stem-cell transplantation (HSCT) is, at present, the only potentially
curative therapy for myelofibrosis (MF). Despite many improvements, outcomes of HSCT are …

Allogeneic hematopoietic stem-cell transplantation for myelofibrosis

L Zhang, F Yang, S Feng - Therapeutic Advances in …, 2020 - journals.sagepub.com
Myelofibrosis is one of the Philadelphia chromosome (Ph)-negative myeloproliferative
neoplasms with heterogeneous clinical course. Though many treatment options, including …

Stem cell transplant for the treatment of myelofibrosis

L Mannelli, P Guglielmelli… - Expert review of …, 2020 - Taylor & Francis
Introduction: Allogeneic hematopoietic stem cell transplantation (HSCT) remains the
cornerstone of curative approach to myelofibrosis (MF), although it is burdened by not …

Transplantation for myelofibrosis patients in the ruxolitinib era: a registry study from the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire

S Villar, S Chevret, X Poire, M Joris… - Bone Marrow …, 2024 - nature.com
In this SFGM-TC registry study, we report the results after stem cell transplantation (HSCT) in
305 myelofibrosis patients, in order to determine potential risk factors associated with …

[HTML][HTML] Peritransplantation use of ruxolitinib in myelofibrosis

U Ibrahim, GEM Petrone, J Mascarenhas… - Biology of Blood and …, 2020 - Elsevier
Ruxolitinib is an oral JAK1/2 inhibitor that is approved for use in patients with intermediate
and high-risk myelofibrosis (MF) based on its proven spleen and symptom burden reduction …

[HTML][HTML] Ruxolitinib for patients with primary or secondary myelofibrosis before allogeneic hematopoietic stem cell transplantation (allo-HSCT): a retrospective study of …

D Lebon, MT Rubio, F Legrand, JJ Kiladjian, M Mohty… - Blood, 2013 - Elsevier
Up to now allo-HSCT is the only curative treatment for patients with myelofibrosis
(MF)(Ballen, et al, Guardiola, et al 1999, Kroger, et al 2007, Robin, et al 2011). The …

[HTML][HTML] Ruxolitinib prior to allogeneic stem cell transplantation does not adversely affect post-transplant outcomes

A Hanif, PN Hari, E Atallah, KSB Carlson, MC Pasquini… - Blood, 2014 - Elsevier
INTRODUCTION Allogeneic stem cell transplant (ASCT) is currently the only curative
therapy for myelofibrosis (MF). Ruxolitinib, an inhibitor of the JAK-STAT pathway, has been …

[HTML][HTML] Haploidentical hematopoietic cell transplantation for myelofibrosis in the ruxolitinib era

M Gambella, S Bregante, AM Raiola, R Varaldo… - … and Cellular Therapy, 2023 - Elsevier
Haploidentical stem cell transplantation is a viable strategy in the absence of an HLA-
identical donor, but in myelofibrosis (MF), concerns may rise due to the risk of graft failure …