The RNA-binding protein ProQ promotes antibiotic persistence in Salmonella
A Rizvanovic, C Michaux, M Panza, Z Iloglu, S Helaine… - MBio, 2022 - Am Soc Microbiol
Bacterial populations can survive exposure to antibiotics through transient phenotypic and
gene expression changes. These changes can be attributed to a small subpopulation of …
gene expression changes. These changes can be attributed to a small subpopulation of …
Saturation mutagenesis charts the functional landscape of Salmonella ProQ and reveals a gene regulatory function of its C-terminal domain
A Rizvanovic, J Kjellin, F Söderbom… - Nucleic acids …, 2021 - academic.oup.com
The global RNA-binding protein ProQ has emerged as a central player in post-
transcriptional regulatory networks in bacteria. While the N-terminal domain (NTD) of ProQ …
transcriptional regulatory networks in bacteria. While the N-terminal domain (NTD) of ProQ …
The major RNA-binding protein ProQ impacts virulence gene expression in Salmonella enterica serovar Typhimurium
AJ Westermann, E Venturini, ME Sellin, KU Förstner… - MBio, 2019 - Am Soc Microbiol
FinO domain proteins such as ProQ of the model pathogen Salmonella enterica have
emerged as a new class of major RNA-binding proteins in bacteria. ProQ has been shown to …
emerged as a new class of major RNA-binding proteins in bacteria. ProQ has been shown to …
ProQ-dependent activation of Salmonella virulence genes mediated by post-transcriptional control of PhoP synthesis
S Bergman, L Andresen, J Kjellin, Y Martinez Burgo… - Msphere, 2024 - Am Soc Microbiol
Gastrointestinal disease caused by Salmonella enterica is associated with the pathogen's
ability to replicate within epithelial cells and macrophages. Upon host cell entry, the bacteria …
ability to replicate within epithelial cells and macrophages. Upon host cell entry, the bacteria …
[HTML][HTML] Global maps of ProQ binding in vivo reveal target recognition via RNA structure and stability control at mRNA 3′ ends
The conserved RNA-binding protein ProQ has emerged as the centerpiece of a previously
unknown third large network of post-transcriptional control in enterobacteria. Here, we have …
unknown third large network of post-transcriptional control in enterobacteria. Here, we have …
Grad-seq guides the discovery of ProQ as a major small RNA-binding protein
A Smirnov, KU Förstner, E Holmqvist… - Proceedings of the …, 2016 - National Acad Sciences
The functional annotation of transcriptomes and identification of noncoding RNA (ncRNA)
classes has been greatly facilitated by the advent of next-generation RNA sequencing …
classes has been greatly facilitated by the advent of next-generation RNA sequencing …
Genetic identification of the functional surface for RNA binding by Escherichia coli ProQ
S Pandey, CM Gravel, OM Stockert… - Nucleic acids …, 2020 - academic.oup.com
Abstract The FinO-domain-protein ProQ is an RNA-binding protein that has been known to
play a role in osmoregulation in proteobacteria. Recently, ProQ has been shown to act as a …
play a role in osmoregulation in proteobacteria. Recently, ProQ has been shown to act as a …
RNA chaperones step out of Hfq's shadow
The stability and function of regulatory small RNAs (sRNAs) often require a specialized RNA-
binding protein called an RNA chaperone. Recent findings show that proteins containing a …
binding protein called an RNA chaperone. Recent findings show that proteins containing a …
The FinO/ProQ-like protein PA2582 impacts antimicrobial resistance in Pseudomonas aeruginosa
A Cianciulli Sesso, A Resch, I Moll, U Bläsi… - Frontiers in …, 2024 - frontiersin.org
Bacteria employ small regulatory RNAs (sRNA) and/or RNA binding proteins (RBPs) to
respond to environmental cues. In Enterobacteriaceae, the FinO-domain containing RBP …
respond to environmental cues. In Enterobacteriaceae, the FinO-domain containing RBP …
Scanning mutagenesis of RNA-binding protein ProQ reveals a quality control role for the Lon protease
The FinO-domain protein ProQ belongs to a widespread family of RNA-binding proteins
(RBPs) involved in gene regulation in bacterial chromosomes and mobile elements. While …
(RBPs) involved in gene regulation in bacterial chromosomes and mobile elements. While …