[HTML][HTML] Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
[HTML][HTML] Immunobiology of atherosclerosis: a complex net of interactions
B Herrero-Fernandez, R Gomez-Bris… - International Journal of …, 2019 - mdpi.com
Cardiovascular disease is the leading cause of mortality worldwide, and atherosclerosis the
principal factor underlying cardiovascular events. Atherosclerosis is a chronic inflammatory …
principal factor underlying cardiovascular events. Atherosclerosis is a chronic inflammatory …
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity
P Roy, M Orecchioni, K Ley - Nature Reviews Immunology, 2022 - nature.com
Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …
preclinical models and emerging evidence in humans have established the crucial roles of …
[HTML][HTML] Immunity, atherosclerosis and cardiovascular disease
J Frostegård - BMC medicine, 2013 - Springer
Atherosclerosis, the major cause of cardiovascular disease (CVD), is a chronic inflammatory
condition with immune competent cells in lesions producing mainly pro-inflammatory …
condition with immune competent cells in lesions producing mainly pro-inflammatory …
The interplay of lipids, lipoproteins, and immunity in atherosclerosis
Abstract Purpose of Review Atherosclerosis is an inflammatory disorder of the arterial wall,
in which several players contribute to the onset and progression of the disease. Besides the …
in which several players contribute to the onset and progression of the disease. Besides the …
[HTML][HTML] The why and how of adaptive immune responses in ischemic cardiovascular disease
Atherosclerotic cardiovascular disease is a major cause of disability and death worldwide.
Most therapeutic approaches target traditional risk factors but ignore the fundamental role of …
Most therapeutic approaches target traditional risk factors but ignore the fundamental role of …
[HTML][HTML] Immune effector mechanisms implicated in atherosclerosis: from mice to humans
P Libby, AH Lichtman, GK Hansson - Immunity, 2013 - cell.com
According to the traditional view, atherosclerosis results from a passive buildup of
cholesterol in the artery wall. Yet, burgeoning evidence implicates inflammation and immune …
cholesterol in the artery wall. Yet, burgeoning evidence implicates inflammation and immune …
The immune response in atherosclerosis: a double-edged sword
GK Hansson, P Libby - Nature reviews immunology, 2006 - nature.com
Immune responses participate in every phase of atherosclerosis. There is increasing
evidence that both adaptive and innate immunity tightly regulate atherogenesis. Although …
evidence that both adaptive and innate immunity tightly regulate atherogenesis. Although …
Targeting the Immune System in Atherosclerosis: JACC State-of-the-Art Review
TX Zhao, Z Mallat - Journal of the American College of Cardiology, 2019 - jacc.org
Atherosclerosis has long been known as an inflammatory disease. However, whether
targeting inflammation improves outcomes was unproven until the recent results of CANTOS …
targeting inflammation improves outcomes was unproven until the recent results of CANTOS …
Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect?
Data from basic science experiments is overwhelmingly supportive of the causal role of
immune‐inflammatory response (s) at the core of atherosclerosis, and therefore, the …
immune‐inflammatory response (s) at the core of atherosclerosis, and therefore, the …