DJ-1 is one of the causative genes of early-onset familial Parkinson's disease (PD). As a
result, DJ-1 influences the pathogenesis of sporadic PD. DJ-1 has various physiological …

Parkinson's disease (PD) is the most common movement disorder characterized by
dopaminergic dysfunction and degeneration. The cause of most PD cases is unknown …

DJ-1 is one of the causative genes for early onset familiar Parkinson's disease (PD) and is
also considered to influence the pathogenesis of sporadic PD. DJ-1 has various …

Loss-of-function mutations in the DJ-1 gene are linked to rare autosomal recessive forms of
parkinsonism. In Drosophila, two DJ-1 orthologs have been identified, DJ-1α and DJ-1β …

Mutations in the DJ-1 gene cause autosomal recessive, early-onset Parkinsonism. The DJ-1
protein exerts a protective role against oxidative stress damage, working as a cellular …

Mutations in the DJ-1 gene are associated with rare forms of autosomal recessive early-
onset Parkinson's disease (PD). Although the precise physiological function of DJ-1 remains …

Parkinson's disease (PD) is a progressive movement disorder caused by the selective and
massive loss of dopaminergic neurons (DA) in the substantia nigra pars compacta (SNc). DJ …

Parkinson's disease (PD) is a common neurodegenerative disorder that displays both
sporadic and inherited forms [1]. Exposure to several common environmental toxins acting …

The loss of dopaminergic neurons in the substantia nigra is the pathological hallmark of
Parkinson's disease (PD). While the etiology of sporadic PD remains elusive, an inherited …

DJ-1 is linked to an early-onset autosomal recessive Parkinson's disease (PD) characterized
primarily by selective loss of dopaminergic (DA) neurons, which results in motor …