Transgenic expression of Nix converts genetic females into males and allows automated sex sorting in Aedes albopictus

C Lutrat, RP Olmo, T Baldet, J Bouyer… - Communications …, 2022 - nature.com
Aedes albopictus is a major vector of arboviruses. Better understanding of its sex
determination is crucial for developing mosquito control tools, especially genetic sexing …

The Nix locus on the male-specific homologue of chromosome 1 in Aedes albopictus is a strong candidate for a male-determining factor

LM Gomulski, M Mariconti, A Di Cosimo, F Scolari… - Parasites & vectors, 2018 - Springer
Background Global concern over the rapid expansion of the Asian tiger mosquito, Aedes
albopictus, and its vector competence has highlighted an urgent need to improve currently …

Nix alone is sufficient to convert female Aedes aegypti into fertile males and myo-sex is needed for male flight

A Aryan, MAE Anderson, JK Biedler… - Proceedings of the …, 2020 - National Acad Sciences
A dominant male-determining locus (M-locus) establishes the male sex (M/m) in the yellow
fever mosquito, Aedes aegypti. Nix, a gene in the M-locus, was shown to be a male …

Partial masculinization of Aedes aegypti females by conditional expression of Nix

BB Kojin, E Jakes, JK Biedler, Z Tu… - PLoS Neglected …, 2022 - journals.plos.org
Background Aedes aegypti, the main vector of dengue, yellow fever, and other arboviruses
thrives in tropical and subtropical areas around the globe putting half of the world's …

The sequence of a male-specific genome region containing the sex determination switch in Aedes aegypti

J Turner, R Krishna, AE Van't Hof, ER Sutton… - Parasites & vectors, 2018 - Springer
Background Aedes aegypti is the principal vector of several important arboviruses. Among
the methods of vector control to limit transmission of disease are genetic strategies that …

[HTML][HTML] Nix is a male-determining factor in the Asian tiger mosquito Aedes albopictus

P Liu, B Jin, X Li, Y Zhao, J Gu, JK Biedler, ZJ Tu… - Insect biochemistry and …, 2020 - Elsevier
The initial signal that governs sex determination is highly variable among insects. A
homolog of Nix, the male-determining factor in Aedes aegypti, was previously found in the …

Joint FAO/IAEA Coordinated Research Project on “Exploring genetic, molecular, mechanical and behavioural methods of sex separation in mosquitoes”–an …

K Bourtzis, ZJ Tu - Parasites & Vectors, 2018 - Springer
Ndo et al.[7] report the isolation, establishment and the characterization of a temperature-
sensitive lethal (tsl) mutant strain in An. arabiensis and describe its potential use for the …

Nix confers heritable sex-conversion in Aedes aegypti and myo-sex is needed for male flight

A Aryan, M Anderson, JK Biedler, Y Qi, JM Overcash… - bioRxiv, 2019 - biorxiv.org
A dominant and hemizygous male-determining locus (M locus) establishes the male sex
(M/m) in the yellow fever mosquito, Aedes aegypti. Nix is a male-determining factor (M …

Combining two genetic sexing strains allows sorting of non-transgenic males for Aedes genetic control

C Lutrat, M Burckbuchler, RP Olmo, R Beugnon… - Communications …, 2023 - nature.com
Chemical control of disease vectoring mosquitoes Aedes albopictus and Aedes aegypti is
costly, unsustainable, and increasingly ineffective due to the spread of insecticide …

Mechanisms of sex determination and transmission ratio distortion in Aedes aegypti

KP Hoang, TM Teo, TX Ho, VS Le - Parasites & vectors, 2016 - Springer
Background More effective mosquito control strategies are urgently required due to the
increasing prevalence of insecticide resistance. The sterile insect technique (SIT) and the …