Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal
tract that encompass two main phenotypes, namely Crohn's disease and ulcerative colitis …

The human epigenome may link environmental exposures and commensal microbiota
changes to host pathology in respect to the developmental origins of inflammatory bowel …

It is generally agreed that environmental factors trigger the onset and cause flares of
inflammatory bowel disease. Although we have learned much about genetic susceptibility …

Recent advances in our understanding of the pathogenesis of inflammatory bowel disease
(IBD) have highlighted the complex interplay between the genome, the epigenome, and the …

Epigenetic alterations may provide important insights into gene-environment interaction in
inflammatory bowel disease (IBD). Here we observe epigenome-wide DNA methylation …

Environmental triggers is part of five focus areas of the Challenges in IBD research
document, which also includes preclinical human IBD mechanisms, novel technologies …

Inflammatory bowel diseases (IBD) represent a growing public health concern due to
increasing incidence worldwide. The current notion on the pathogenesis of IBD is that …

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the colonic mucosa.
Environmental factors, genetics, intestinal microbiota, and the immune system are all …

Background Genetic studies have been tremendously successful in identifying genomic
regions associated with a wide variety of phenotypes, although the success of these studies …

Inflammatory bowel disease (IBD) has as a main characteristic the exacerbation of the
immune system against enterocytes, compromising the individual's intestinal microbiota …