Developing Implantable Hydrogel-Based Sensors to Measure Biomarkers in Synovial Joint Fluid Using Plain Radiography

UN Wijayaratna - 2022 - tigerprints.clemson.edu
The goal of my dissertation research is to develop implantable sensors that attach to
prosthesis prior to implantation and measures biomarkers of infection in joint fluid in order to …

Synovial fluid pH sensor for early detection of prosthetic hip infections

UN Wijayaratna, SD Kiridena, JD Adams… - Advanced functional …, 2021 - Wiley Online Library
An implantable sensor developed to measure synovial fluid pH for noninvasive early
detection and monitoring of hip infections using standard‐of‐care plain radiography is …

X‐Ray Visualized Synovial Fluid Carbon Dioxide Sensor for Early Detection of Prosthetic Hip Infections

SD Kiridena, UN Wijayaratna, R Wang… - Advanced Sensor …, 2023 - Wiley Online Library
A radiographically visualized implantable dissolved carbon dioxide (CO2) sensor is
developed to non‐invasively detect and monitor hip infections. The sensor is based on a pH …

An implanted pH sensor read using radiography

M Arifuzzaman, PW Millhouse, Y Raval, TB Pace… - Analyst, 2019 - pubs.rsc.org
A biomedical sensor was developed to measure local pH near orthopedic implants to detect
and study implant-associated infection. The sensor is read using plain radiography, a …

[PDF][PDF] SENSOR FOR EARLY DETECTION OF PROSTHETIC JOINT INFECTIONS

ANXRAYIF BEAD - TigerPrint s, 2022 - tigerprints.clemson.edu
Prosthetic joint infections are a major complication for patients undergoing joint surgery.
Available diagnostic tests are nonspecific to prosthetic joint infections and based on serum …

A smart polymer hydrogel as a chemical sensor on biomedical implant

M Arifuzzaman, C Behrend, J DesJardins, JN Anker - 2016 - tigerprints.clemson.edu
Orthopedic implants are manufactured to support on healing fractured bones. In United
States, over 2 million fracture fixation devices, including intra-medullary nails, external …

Acidity Is an Excellent Marker of Infection in Hip and Knee Arthroplasty

T Judl, S Popelka, E Tomšík, M Hrubý, M Daniel… - Journal of Clinical …, 2024 - mdpi.com
Background: The diagnosis of joint replacement infection is a difficult clinical challenge that
often occurs when the implant cannot be salvaged. We hypothesize that the pH value of …

Engineering approaches for the detection and control of orthopaedic biofilm infections

GD Ehrlich, P Stoodley, S Kathju, Y Zhao… - Clinical Orthopaedics …, 2005 - journals.lww.com
Artificial joints are subject to chronic infections associated with bacterial biofilms, which only
can be eradicated by the traumatic removal of the implant followed by sustained intravenous …

Development of intelligent implants for biofilm prevention in orthopedic prostheses

GD Ehrlich, V Weedn, S Kathju… - Bio-, Micro-, and …, 2003 - ieeexplore.ieee.org
A multidisciplinary multiinstitutional group of investigators composed of microbiologists,
MEMs scientists, and electrical engineers has been assembled to work on the design and …

High-fidelity point-of-care diagnostic test for periprosthetic joint infection: commentary on an article by Thorsten Gehrke, MD, et al.:“The accuracy of the alpha defensin …

GD Ehrlich, MP Palmer - JBJS, 2018 - journals.lww.com
Pain following arthroplasty presents the physician with a challenging diagnostic dilemma,
and the diagnosis of periprosthetic joint infection is traumatic for the patient and surgeon …